Surgical treatment with spinal instrumentation for pyogenic spondylodiscitis due to methicillin-resistant Staphylococcus aureus (MRSA): a report of five cases

Archives of Orthopaedic and Trauma Surgery
Takahiro MasudaKatsuji Shimizu

Abstract

The treatment of methicillin-resistant Staphylococcus aureus (MRSA) spondylodiscitis is reported to be far more difficult than that of non-MRSA spondylodiscitis. At present, there seems to be no standard protocol for the treatment of MRSA spondylodiscitis cases in which conservative management has failed. Between 1998 and 2001, five patients (aged 48-73 years; average: 63.8 years; SD: 9.9) with MRSA spondylodiscitis were treated surgically after conservative treatment had failed. Posterior spinal instrumentation was performed for all five patients, three of whom also underwent anterior debridement and bone graft. All the patients had neurological deficits and severe pain. To assess the invasiveness of the operation, we evaluated operating time, blood loss, and complications. Pain (verbal rating scale; VRS), neurological status (Frankel type), activities of daily living (ADL) (the Barthel index), WBC, CRP, and ESR in the preoperative, postoperative and final follow-up periods were used to evaluate the surgical outcomes. Although we encountered several postoperative complications including deep wound infections, at the final follow-up visit, the neurological deficits, activities of daily living, Barthel index, and VRS had improve...Continue Reading

References

Feb 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·D T Wade, R L Hewer
Feb 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A J TordaR Bradbury
Jun 1, 1997·Journal of Neurosurgery·A D LeviV K Sonntag
Nov 20, 1998·Journal of Pediatric Orthopedics·G SzökeK Dabney
Dec 16, 1998·Southern Medical Journal·S D HodgesN G Kurzynske
May 8, 1999·Neurosurgery·A R RezaiP R Cooper
Jun 28, 2000·Spine·A G HadjipavlouA J Muffoletto
Mar 10, 2001·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·T KimA E Simor
Apr 3, 2002·Journal of Spinal Disorders & Techniques·Hwan T HeeDavid Pienkowski
Dec 21, 2002·Diagnostic Microbiology and Infectious Disease·Helio S SaderUNKNOWN SENTRY Participants Group (Latin America)
Jun 28, 2003·British Journal of Nursing : BJN·Rebecca Myatt, Sue Langley
Jul 16, 2003·Current Opinion in Infectious Diseases·Rafael CantónFernando Baquero
Sep 10, 2003·International Orthopaedics·C C TaiS P F Hughes

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Citations

Nov 16, 2006·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Wei-Hua ChenLi-Yang Dai
Aug 29, 2006·Current Infectious Disease Reports·Frank L AcostaChristopher P Ames
Jun 6, 2008·Current Opinion in Rheumatology·Irene S KourbetiDimitrios T Boumpas
Jun 3, 2010·Journal of Neurosurgery. Spine·Mahmoud RayesHazem A Eltahawy
Oct 15, 2013·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Wei-Hua ChenGuo-Hua Lü
Apr 8, 2014·The Spine Journal : Official Journal of the North American Spine Society·Ehab ShibanFlorian Ringel
Aug 13, 2010·Journal of Infection and Public Health·G S SkafS S Kanj
May 26, 2012·The Journal of Bone and Joint Surgery. British Volume·K FushimiK Shimizu

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