Surgical ventricular restoration plus mitral valve repair in patients with ischaemic heart failure: risk factors for early and mid-term outcomes†

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Serenella CastelvecchioLorenzo Menicanti

Abstract

To assess the early and mid-term outcomes and related predictors in a consecutive series of patients who underwent surgical ventricular restoration (SVR) combined with additional mitral valve (MV) repair. From January 2001 to October 2014, 626 patients underwent SVR; of these, 175 (28%, median age 65) had an additional MV repair. Anterior, inferior or diffuse remodelling was present in 124 (71%), 41 (23%) and 10 (6%) patients, respectively. The median ejection fraction was 30%, whereas mitral regurgitation grade was 3.3 ± 0.8. Multivariable logistic regression and Cox regression analyses were used to identify predictors of early and mid-term mortality. Operative death occurred in 25 patients (14.3%). Independent predictors of early mortality were age, creatinine and ejection fraction score [odds ratio (OR) = 5.1, 95% confidence interval (CI) 2.5-10.3], previous stroke (OR = 8.0, 95% CI 1.5-44), unstable angina (OR = 8.8, 95% CI 1.5-53) and diffuse remodelling (OR = 5.8, 95% CI 1.02-33). Average follow-up was 42 ± 37 months. The actuarial survival rate of the whole patient population at 3, 5 and 8 years was 72 ± 4, 65 ± 4 and 45 ± 6%, respectively. Risk factors for late mortality were preoperative creatinine (OR = 2.6, 95% CI 1....Continue Reading

References

Jun 14, 2002·The Journal of Thoracic and Cardiovascular Surgery·L MenicantiUNKNOWN RESTORE Group
Jul 31, 2007·The Journal of Thoracic and Cardiovascular Surgery·Lorenzo MenicantiMarisa Di Donato
Nov 21, 2007·The Journal of Thoracic and Cardiovascular Surgery·Marisa Di DonatoLorenzo Menicanti
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Sep 28, 2010·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·UNKNOWN Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for CardDavid Taggart
Nov 1, 2011·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Sandro GelsominoJos Maessen
Nov 19, 2014·The New England Journal of Medicine·Peter K SmithUNKNOWN Cardiothoracic Surgical Trials Network Investigators
Dec 10, 2014·The Annals of Thoracic Surgery·Andrea GarattiLorenzo Menicanti
Feb 19, 2015·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Serenella CastelvecchioUNKNOWN Surgical and Clinical Outcome Research (SCORE) Group

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Citations

May 24, 2017·European Heart Journal Supplements : Journal of the European Society of Cardiology·Serenella CastelvecchioLorenzo Menicanti
Oct 14, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Suguru OhiraHitoshi Yaku
May 21, 2019·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Serenella CastelvecchioLorenzo Menicanti
Oct 17, 2020·Indian Journal of Thoracic and Cardiovascular Surgery : Official Organ, Association of Thoracic and Cardiovascular Surgeons of India·Srilakshmi Mandayam AdhyapakTinku Thomas
Sep 9, 2021·Journal of Cardiac Surgery·Ali Fatehi HassanabadImtiaz S Ali

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