Surgical vs medical management of chronic open-angle glaucoma

American Journal of Ophthalmology
W C StewartC LoPresto

Abstract

We studied patients with chronic open-angle glaucoma who had similar intraocular pressures to determine whether surgical or medical therapy is more effective in preventing progressive, long-term, glaucomatous damage. Included in this study were patients with chronic open-angle glaucoma who were followed for 3 years or longer and were treated, through either medical or surgical therapy, by adjusting intraocular pressure to 18 mm Hg or less as a therapeutic end point. We studied 31 matched pairs of patients in which one member was treated by surgery and one member had medical treatment. In every pair, we matched each patient individually by age, race, and intraocular pressure. For the matched pairs of patients in this study, the mean intraocular pressure following initiation of treatment was 13.5 and 13.1 mm Hg for the surgically and medically treated groups, respectively (P = .475). This study found no difference between groups in the incidence of glaucomatous progression following surgical (n = 3) or medical (n = 3) therapy (P > .99, McNemar's test) for an average follow-up of 40.0 +/- 10.0 and 43.4 +/- 8.4 months in the medical and surgical groups respectively. The glaucoma of three patients progressed on the basis of reduced ...Continue Reading

References

Mar 1, 1972·The British Journal of Ophthalmology·R J Smith
Sep 1, 1982·Ophthalmology·W M Grant, J F Burke
Aug 15, 1993·American Journal of Ophthalmology·W C StewartG Sethuraman
Apr 1, 1963·Archives of Ophthalmology·L E ZIMMERMAN

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Citations

Dec 17, 2002·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Algis J Vingrys
Oct 6, 2000·American Journal of Ophthalmology·W C StewartJ B Cantrell
May 30, 2002·American Journal of Ophthalmology·Martin B WaxRobert N Weinreb
Feb 9, 2005·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Pia EhrnroothLeila Laatikainen
Feb 6, 2008·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·D E KruseK W Ferrara
Mar 1, 2006·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·William C StewartJeanette A Stewart
Jul 10, 2001·Journal of Glaucoma·G L Spaeth, E Mutlukan
Feb 24, 2009·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Ahmad Tajudin Liza SharminiWilliam C Stewart
Feb 24, 2009·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Gong Je SeongWilliam C Stewart
Sep 28, 2013·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Andrea RussoLuciano Quaranta
Jan 23, 2003·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Felipe A MedeirosRemo Susanna
May 13, 1999·Postgraduate Medical Journal·D A Infeld, J G O'Shea
Oct 27, 2009·Journal of Glaucoma·George L SpaethParul Ichhpujani
Jan 8, 2004·Journal of Cataract and Refractive Surgery·Bruce Drum, Gene Hilmantel
Sep 14, 2012·The Cochrane Database of Systematic Reviews·Jennifer BurrAnja Tuulonen
Dec 17, 2002·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·John G O'SheaRobert B Harvey

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