Surveillance and clinical characterization of influenza in a university cohort in Singapore

PloS One
Aidan Lyanzhiang TanBoon-Huan Tan

Abstract

Southeast Asia is a potential locus for the emergence of novel influenza strains. However, information on influenza within the region is limited. This study was to determine the proportion of influenza-like illness (ILI) caused by influenza A and B viruses in a university cohort in Singapore, identify important distinctive clinical features of influenza infection and potential factors associated with influenza infection compared with other causes of ILI. A surveillance study was conducted from 2007 to 2009, at the University Health and Wellness Centre, National University of Singapore (NUS). Basic demographic information and nasopharyngeal swabs were collected from consenting students and staff with ILI, with Influenza A and B identified by both culture and molecular methods. Proportions of influenza A and B virus infections in subjects with ILI were 153/500 (30.6%) and 11/500 (2.2%) respectively. The predominant subtype was A/H1N1, including both the seasonal strain (20/153) and the pandemic strain (72/153). The clinical symptom of fever was more common in subjects with laboratory confirmed influenza than other ILIs. On-campus hostel residence and being a student (compared with staff) were associated with increased risk of lab...Continue Reading

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Citations

Jan 7, 2017·PloS One·Ramandeep Kaur VirkPaul Anantharajah Tambyah
Nov 12, 2017·Influenza and Other Respiratory Viruses·Lance JenningsJing Chen

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