Surveillance of Circulating Bordetella pertussis Strains in Europe during 1998 to 2015

Journal of Clinical Microbiology
Alex-Mikael BarkoffQiushui He

Abstract

One reason for increased pertussis incidence is the adaptation of Bordetella pertussis to vaccine-induced immunity by modulating its genomic structure. This study, EUpert IV, includes 265 isolates collected from nine European countries during 2012 to 2015 (n = 265) and compares the results to previous EUpert I to III studies (1998 to 2009). The analyses included genotyping, serotyping, pulsed-field gel electrophoresis (PFGE), and multilocus variable-number tandem-repeat analysis (MLVA). Genotyping results showed only small variations among the common virulence genes of B. pertussis The frequencies of serotypes Fim2 and Fim3 varied among the four collections. Genomic analyses showed that MLVA type 27 increased to 80% between the periods of 1998 to 2001 and 2012 to 2015. Two PFGE profiles, BpSR3 (29.4%) and BpSR10 (27.2%), constituted more than 50% of the circulating isolates in the present collection. Our study indicates that the European B. pertussis population is changing and became more homogenous after the introduction of acellular pertussis vaccines.

References

May 5, 2000·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·F R MooiN Guiso
Jul 10, 2004·Journal of Clinical Microbiology·Abdolreza AdvaniHans Hallander
Jun 16, 2005·Journal of Clinical Microbiology·S C M van AmersfoorthF R Mooi
Sep 26, 2008·BMC Microbiology·Eriikka HeikkinenQiushui He
Sep 16, 2009·Emerging Infectious Diseases·Frits R MooiJussi Mertsola
Jan 19, 2010·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Hans O HallanderEva Netterlid
Aug 23, 2012·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·T KallonenQ He
Aug 24, 2012·Clinical and Vaccine Immunology : CVI·Alex-Mikael BarkoffQiushui He
Oct 3, 2012·PloS One·Marjolein van GentFrits R Mooi
Feb 15, 2013·Epidemiology and Infection·F R MooiH E De Melker
Jul 18, 2014·Journal of Clinical Microbiology·Katherine E BowdenMaria Lucia Tondella
Dec 21, 2014·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M van GentF R Mooi
Jul 26, 2015·Pathogens and Disease·Alex-Mikael BarkoffQiushui He
Jan 31, 2016·The Journal of Infection·Azadeh SafarchiRuiting Lan
Sep 16, 2016·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Tine DalbySteen Hoffmann
Feb 9, 2017·Journal of Bacteriology·Michael R WeigandMargaret M Williams

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Citations

Aug 11, 2018·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Fatemah Sadeghpour HeraviFereshteh Shahcheraghi
Oct 19, 2019·Emerging Infectious Diseases·Francisco CarriquiribordeDaniela Hozbor
Feb 26, 2021·Journal of Clinical Microbiology·Michael R WeigandM Lucia Tondella
Jun 26, 2021·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Azadeh SafarchiRuiting Lan

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