Abstract
The objective was to use population-based electronic health records for surveillance of intrauterine exposures to substances of abuse, including opioids, and to monitor changes in exposure rates over time. This retrospective, descriptive analysis utilized geocoded neonatal physician billing records representing intrauterine exposures to substances of abuse detected through universal maternal drug testing. Census tract-level exposure rates were identified among the newborn population of Hamilton County, Ohio between 2014 and 2016. Among 27,896 newborns, the authors detected an intrauterine opioid exposure rate of 37.9 per 1000 infants, with 10.5 per 1000 experiencing severe opioid withdrawal (neonatal abstinence syndrome). Individual data were mapped to 222 US census tracts. Tract-level opioid exposure rates ranged from 0.0 to 607.1 (median: 32.9) per 1000 live births. Secondary use of electronic health record data has potential to aid in intrauterine opioid exposure and other public health surveillance efforts without disrupting clinical workflows or placing an additional burden on limited resources. Surveillance of intrauterine opioid exposures may inform stakeholders and enable targeting of interventions and prevention strate...Continue Reading
References
May 2, 2012·JAMA : the Journal of the American Medical Association·Stephen W PatrickMatthew M Davis
Jul 30, 2014·Pediatrics·Prabhakar Kocherlakota
Dec 3, 2014·The Journal of Pediatrics·Scott L WexelblattJames M Greenberg
Apr 29, 2015·The New England Journal of Medicine·Veeral N ToliaAlan R Spitzer
May 1, 2015·Journal of Perinatology : Official Journal of the California Perinatal Association·S W PatrickW O Cooper
Sep 16, 2015·Pediatrics·Eric S HallUNKNOWN OCHNAS Consortium
Oct 20, 2015·The Journal of Pediatrics·Eric S HallScott L Wexelblatt
Feb 18, 2016·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·Meagan E StablerLaura R Lander
Aug 12, 2016·MMWR. Morbidity and Mortality Weekly Report·Jean Y KoWanda D Barfield
Sep 27, 2016·JAMA Pediatrics·Joshua D BrownJeffery C Talbert
Dec 13, 2016·JAMA Pediatrics·Nicole L G VillapianoStephen W Patrick
Dec 22, 2016·The New England Journal of Medicine·Karen McQueen, Jodie Murphy-Oikonen
Feb 22, 2017·Pediatrics·Stephen W PatrickUNKNOWN COMMITTEE ON SUBSTANCE USE AND PREVENTION
May 12, 2017·Journal of Perinatology : Official Journal of the California Perinatal Association·E S HallJ M Greenberg
Jul 8, 2017·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·Joshua D BrownJeffery C Talbert
Oct 21, 2017·The Journal of Pediatrics·Sunah S HwangMilton Kotelchuck
Citations
Jun 13, 2018·Population Health Management·Eric S HallScott L Wexelblatt
May 17, 2019·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Somayyeh ZakerabasaliShahabeddin Abhari
Oct 14, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Somayyeh ZakerabasaliAzadeh Sayarifard
Jan 4, 2020·Pediatrics·Neera K GoyalEsther K Chung