Surveillance of Pseudomonas aeruginosa-isolates in a neonatal intensive care unit over a one year-period

International Journal of Hygiene and Environmental Health
Lutz Thomas ZabelRangmar Goelz

Abstract

Outbreaks of gram-negative bacteria such as Pseudomonas aeruginosa in neonatal intensive care units (NICU) can be life-threatening to pre-term infants, which are highly susceptible to serious infections with bacteria. Forty-two ventilated neonates in the NICU of the University Children's Hospital of Tuebingen were found to be colonized (n = 40) or infected (n = 2) with P. aeruginosa within a sampling period of one year. To investigate the colonization patterns and identify potential outbreak sources, epidemiological investigations, environmental surveillance and typing by serotyping and pulsed-field gel electrophoresis of the recovered isolates were performed. The investigation demonstrated a genetically related cluster of P. aeruginosa isolates during the surveillance period in 39 neonates and a second cluster at the end of the period in two neonates. A third strain representing a genetically distinct group was found in only one patient. Environmental investigations demonstrated the presence of P. aeruginosa in the ventilation equipment of 22 patients: binasal prongs (n = 22), water reservoir (n = 9), and heater (n = 1). In one case, P. aeruginosa was found in breast milk. Other environmental investigations revealed no P. aeru...Continue Reading

References

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Citations

Oct 20, 2006·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·P GérardinP-Y Robillard
Dec 6, 2005·International Journal of Hygiene and Environmental Health·Berit SchulteStefan Borgmann
Sep 13, 2018·Journal of Perinatology : Official Journal of the California Perinatal Association·Ülle ParmHiie Soeorg

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