Surveillance of Salmonella enterica serovar  Typhi in Colombia, 2012-2015

PLoS Neglected Tropical Diseases
Paula Diaz-GuevaraStephen Baker

Abstract

Salmonella Typhi (S. Typhi) is the causative agent of typhoid fever; a systemic disease affecting ~20 million people per year globally. There are little data regarding the contemporary epidemiology of typhoid in Latin America. Consequently, we aimed to describe some recent epidemiological aspects of typhoid in Colombia using cases reported to the National Public Health Surveillance System (Sivigila) between 2012 and 2015. Over the four-year reporting period there were 836 culture confirmed cases of typhoid in Colombia, with the majority (676/836; 80.1%) of reported cases originated from only seven departments. We further characterized 402 S. Typhi isolates with available corresponding data recovered from various departments of Colombia through antimicrobial susceptibility testing and molecular subtyping. The majority (235/402; 58.5%) of these typhoid cases occurred in males and were most commonly reported in those aged between 10 and 29 years (218/402; 54.2%); there were three (0.74%) reported fatalities. The overwhelming preponderance (339/402; 84.3%) of S. Typhi were susceptible to all tested antimicrobials. The most common antimicrobial to which the organisms exhibited non-susceptibility was ampicillin (30/402;7.5%), followe...Continue Reading

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Citations

Sep 17, 2021·PLoS Neglected Tropical Diseases·Paula Diaz GuevaraStephen Baker

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Methods Mentioned

BETA
PCR
genotyping

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ArcGIS
R
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PNLA
Excel
Gelcompare

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