Surveillance of stage I testicular seminoma: British Columbia Cancer Agency Experience 1992 to 2002

Urology
Scott TyldesleyDouglas Wu

Abstract

To review the changes in the use of surveillance in Stage I seminoma in British Columbia during the past decade and to compare the relapse rates provincially against those in published reports. Postorchiectomy surveillance of Stage I seminoma is an alternative to adjuvant radiotherapy. The relapse rate from a pooled surveillance series was 18% at 5 years. We reviewed the British Columbia Cancer Agency Tumour Registry records for all cases registered with a diagnosis of seminoma of the testes referred to the BCCA between 1992 and 2002. Patients not treated with radiotherapy within 4 months of referral were reviewed for patient and disease parameters (age, rete testes invasion, size, lymphatic invasion), relapse, salvage treatment, and survival. A total of 458 patients with Stage I seminoma were identified. Of these, 93 went onto surveillance. The annual percentage of patients going onto surveillance increased from 10% in 1992 to 33% by 2002. The median follow-up was 33 months. The 5-year actuarial relapse-free survival rate was 78%. Relapse was more common in those with known adverse prognostic factors (rete invasion or size greater than 4 cm). The actuarial 5-year relapse free rate was 86%, 71%, and 50% for patients with no ris...Continue Reading

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Citations

Oct 12, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C KollmannsbergerC Nichols
Oct 21, 2009·BJU International·Padraig Warde, Mary Gospodarowicz
Jul 30, 2014·European Urology·Mette Saksø MortensenGedske Daugaard
Nov 30, 2014·Abdominal Imaging·Monica J WoodStephanie A Howard
Jan 8, 2011·Journal of the National Cancer Institute·Peter Chung, Padraig Warde
Aug 20, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Karen E HoffmanAnthony V D'Amico
Oct 12, 2011·Onkologie·Hans Joachim Schmoll, Klaus Heissner

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