Surveillance pouchoscopy for dysplasia: Cleveland Clinic Ileoanal Pouch Anastomosis Database.

The British Journal of Surgery
Amy L LightnerJ Church

Abstract

No formal guidelines exist for surveillance pouchoscopy following ileal pouch-anal anastomosis (IPAA) for ulcerative colitis. All adults who had previously had IPAA for ulcerative colitis, and underwent a pouchoscopy between 1 January 2010 and 1 January 2020, were included. A total of 9398 pouchoscopy procedures were performed in 3672 patients. The majority of the examinations were diagnostic (8082, 86·0 per cent; 3260 patients) and the remainder were for routine surveillance (1316, 14·0 per cent; 412 patients). Thirteen patients (0·14 per cent of procedures) were found to have biopsy-proven neoplasia at the time of pouchoscopy; seven had low-grade dysplasia (LGD) (0·07 per cent; all located in the anal transition zone), none had high-grade dysplasia (HGD) and six (0·06 per cent) had invasive adenocarcinoma (4 in anal transition zone and 6 in pouch). Of the six patients with adenocarcinoma, four had neoplasia at the time of proctocolectomy (2 adenocarcinoma, 1 LGD, 1 HGD); all six were symptomatic with anal bleeding or pelvic pain at the time of pouchoscopy, had a negative surveillance pouchoscopy examination within 2 years of diagnosis of adenocarcinoma, had palpable masses on digital rectal examination, and had visible lesion...Continue Reading

References

Jul 8, 1978·British Medical Journal·A G Parks, R J Nicholls
Mar 1, 1992·Diseases of the Colon and Rectum·D PuthuP Venugopal
Oct 20, 1990·BMJ : British Medical Journal·N A Shepherd
Jan 1, 1987·Diseases of the Colon and Rectum·P R O'ConnellR L Telander
Aug 1, 1995·Diseases of the Colon and Rectum·I C LaveryV W Fazio
Oct 13, 1998·Virchows Archiv : an International Journal of Pathology·M ViethM Stolte
Nov 21, 1998·The British Journal of Surgery·M W Thompson-FawcettN J Mortensen
Aug 7, 2001·Gastroenterology·M W Thompson-FawcettR S McLeod
Jun 6, 2003·International Journal of Colorectal Disease·Cesare HassanSergio Morini
Nov 4, 2004·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·L BörjessonL Hultén
Apr 13, 2007·Diseases of the Colon and Rectum·Naris NilubolJoel J Bauer
Mar 13, 2009·Diseases of the Colon and Rectum·Marco M HeftiThomas A Ullman
Apr 30, 2010·Gut·Stuart R CairnsUNKNOWN Association of Coloproctology for Great Britain and Ireland
Jan 10, 2013·Annals of Surgery·Victor Warren FazioSean T Martin
Oct 1, 2013·Gastroenterology·Lauranne A A P DerikxUNKNOWN Dutch Initiative on Crohn and Colitis
Apr 1, 2014·Inflammatory Bowel Diseases·Francesco SelvaggiGuido Sciaudone
Feb 25, 2015·Gastrointestinal Endoscopy·Loren LaineUNKNOWN SCENIC Guideline Development Panel
Mar 25, 2015·Gastrointestinal Endoscopy·UNKNOWN ASGE Standards of Practice CommitteeJohn M DeWitt
Aug 22, 2015·Journal of Crohn's & Colitis·Vito AnneseUNKNOWN ECCO
Sep 27, 2015·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Lauranne A A P DerikxFrank Hoentjen
Apr 5, 2018·Journal of Crohn's & Colitis·Levente ParragiUNKNOWN Swiss IBD Cohort Study Group

❮ Previous
Next ❯

Citations

Apr 15, 2021·Diseases of the Colon and Rectum·Stefan D HolubarUNKNOWN Prepared on behalf of the Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons
Jul 13, 2021·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Anuradha R Bhama, Muneera R Kapadia
May 16, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Roshani PatelAndrew Latchford

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Invasive Carcinoma

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.

Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.