Surveillance Strategies for Tracking Sepsis Incidence and Outcomes.

The Journal of Infectious Diseases
Claire N ShappellChanu Rhee

Abstract

Sepsis is a leading cause of death and the target of intense efforts to improve recognition, management and outcomes. Accurate sepsis surveillance is essential to properly interpreting the impact of quality improvement initiatives, making meaningful comparisons across hospitals and geographic regions, and guiding future research and resource investments. However, it is challenging to reliably track sepsis incidence and outcomes because sepsis is a heterogeneous clinical syndrome without a pathologic reference standard, allowing for subjectivity and broad discretion in assigning diagnoses. Most epidemiologic studies of sepsis to date have used hospital discharge codes and have suggested dramatic increases in sepsis incidence and decreases in mortality rates over time. However, diagnosis and coding practices vary widely between hospitals and are changing over time, complicating the interpretation of absolute rates and trends. Other surveillance approaches include death records, prospective clinical registries, retrospective medical record reviews, and analyses of the usual care arms of randomized controlled trials. Each of these strategies, however, has substantial limitations. Recently, the US Centers for Disease Control and Pre...Continue Reading

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Citations

Jul 22, 2020·The Journal of Infectious Diseases·Edward J Septimus
Mar 20, 2021·BMJ Open·Carolin Fleischmann-StruzekAndré Scherag
Mar 30, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Brady PageChanu Rhee
Jul 29, 2021·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Sriram Sampath
Jul 15, 2021·Critical Care Medicine·Claire N ShappellChanu Rhee

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