PMID: 9545685Apr 18, 1998Paper

Survey of fungemia cases during the past seventeen years at Teikyo University Hospital

Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases
S KawakamiH Yamaguchi

Abstract

Fungi were isolated from 642 cases (3.5%) of 18,403 blood samples at Teikyo University Hospital during the 17-years period between 1979 and 1995. The number of fungemia cases began to increase around 1985, reached a peak in 1988, and since then, it has been gradually decreasing. The fungal species of isolates were: (1) Candida albicans in 224 cases (34.9%), (2) C. parapsilosis in 149 cases (23.2%), (3) C. tropicalis in 87 cases (13.6%), (4) C. glabrata in 65 cases (10.1%), (5) Hansenula anomala in 58 cases (9.0%), (6) C. guilliermondii in 24 cases (3.7%), (7) C. famata in 14 cases (2.1%), (8) Trichosporon beigelii in 11 cases (1.7%), (9) C. inconspicua in 5 cases (0.8%) and C. lusitaniae in 5 cases (0.8%), and other yeasts in 33 causes (5.1%). The number of isolates of C. albicans has been decreasing since 1989, concomitant with the clinical introduction of fluconazole in this hospital. However, the number of fluconazole-insusceptible fungi such as non-albicans Candida and Trichosporon spp. has increased. Fungemia cases infected concomitantly or sequentially with two or more different fungal species have been found occasionally since 1983 and have shown a high mortality rate. The spectrum of the causative organisms of fungemia ...Continue Reading

Citations

Oct 23, 2012·The Journal of Antimicrobial Chemotherapy·Nicholas D BeydaKevin W Garey
Feb 8, 2005·Journal of Clinical Microbiology·Luis CarrascoMaría Eugenia González
Jul 11, 2006·Journal of Clinical Microbiology·Corrado GirmeniaPietro Martino

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