Survey of microphthalmia in Japan.

Japanese Journal of Ophthalmology
Sachiko NishinaNoriyuki Azuma

Abstract

To report the current status of patients with microphthalmia based on a cross-sectional survey of patient hospital visits. A questionnaire was sent to the departments of ophthalmology in 1,151 major Japanese hospitals to survey the following: the number of patients with microphthalmia who visited the outpatient clinics between January 2008 and December 2009; gender; age; family history; associated ocular anomalies; complications and systemic diseases; surgical treatment; vision and management. A retrospective quantitative registry of 1,254 microphthalmic eyes (851 patients) from 454 hospitals (39.4%) was compiled. Of the patients for whom data were available, 50% ranged in age from 0 to 9 years. The major ocular findings were nanophthalmos, coloboma, and vitreoretinal malformations. Ocular complications frequently developed, including cataracts, glaucoma, and retinal detachment. Surgery was performed in 21.4% of all cases, and systemic diseases were present in 31% of all cases. The vision associated with microphthalmia exceeded 0.1 in about 30% of the eyes. Glasses and low vision aids were used by 21.6% of patients. Patients with microphthalmia often have ocular and systemic anomalies. Early assessment and preservation of visio...Continue Reading

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Citations

Jan 28, 2014·Seminars in Ophthalmology·D Erginturk AcarE S Cakar
Oct 30, 2016·American Journal of Medical Genetics. Part a·Jamile D CorreiaRafael F M Rosa
Jan 18, 2017·European Journal of Human Genetics : EJHG·Rose RichardsonMariya Moosajee
Jan 4, 2020·European Journal of Human Genetics : EJHG·Jonathan EintrachtMariya Moosajee
May 22, 2020·Acta Ophthalmologica·Rezhna Taha NajimMarita Andersson Grönlund
Mar 7, 2021·International Journal of Molecular Sciences·Philippa HardingMariya Moosajee

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