Survey on human papillomavirus/p16 screening use in oropharyngeal carcinoma patients in the United States

Cancer
Asal N ShoushtariPaul W Read

Abstract

Patients with human papillomavirus (HPV)-positive oropharyngeal carcinoma (OC) have better prognosis than patients with HPV-negative OC. The objective of the current study was to assess how different practices across the United States treat patients with OC with respect to screening for HPV DNA or p16. Five hundred forty-two randomly selected radiation oncologists were sent an 11-question survey by email regarding the use of HPV/p16 screening in OC. The questionnaire addressed demographics of the practice, intensity-modulated radiotherapy (IMRT) use, screening practices for HPV DNA or p16, which year this began, the use of HPV or p16 data to direct patient care, and future plans for its use if it had not already been instituted. One hundred ninety-two responses (39.6%) were received. Thirty-five percent of respondents (67 of 188) reported screening for HPV DNA routinely, whereas 4.8% of respondents (9 of 188) reported screening for p16. Of the physicians who did not use screening techniques, 37.2% (44 of 118 respondents) reported future plans to institute these screening techniques, 20% (9 of 45 respondents) stated plans to institute these techniques in the next 6 months, 55.5% (25 of 45 respondents) stated plans to institute t...Continue Reading

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Citations

Jul 1, 2010·The American Journal of Surgical Pathology·James S LewisSamir K El-Mofty
Mar 4, 2014·Archives of Gynecology and Obstetrics·Virginia LozzaMaria Grazia Fallani
Aug 7, 2014·Oral Oncology·Anastasios ManiakasApostolos Christopoulos
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Jun 30, 2012·The American Journal of Surgical Pathology·Richard C JordanMaura L Gillison
Dec 24, 2018·Expert Review of Molecular Diagnostics·Caitlin McMullenJuan C Hernandez-Prera

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