PMID: 22575141May 12, 2012Paper

Survey on the recessive infection of pathogen to hand-foot-mouth disease among healthy adults and children in Guangdong province

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
Ai-ping DengJin-yan Lin

Abstract

To understand the pathogen-carrying status of hand-foot-mouth disease (HFMD) among healthy people in Guangdong province. Stool specimens were collected randomly on 7 age groups from 7 cities in Guangdong province. Real-time RT-PCR was used to detect enterovirus (EV), enterovirus 71 (EV71) and coxsackie virus A16 (CA16). Altogether, 1285 stool specimens were collected. The positive rates of EV71, CA16 and other enterovirus were 0.39% (5/1285), 0.23% (3/1285) and 7.00% (90/1285), respectively. The highest EV71 positive rate (1.79%) was among the 4-6-year-old group, followed by the age group 0 - 3 with positive rate as 0.67%. EV71 was not found among the rest age groups. The highest CA16 positive rate (1.35%) was among the 4 - 6 year-olds group, but the CA16 was not found among the rest age groups. EV71 was only found among native population, with the positive-rate as 0.47%. CA16-positive rate was 0.19% among the native population and 0.85% among floating population, with no significant difference found (P > 0.05). The EV71 positive rate was 0.36% among rural residents and 0.54% among urban residents, but with no significant difference (P > 0.05). All CA16 was found among the urban residents. Recessive infection of EV71 and CA16 w...Continue Reading

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