Survival after massive arsenic poisoning self-treated by high fluid intake

Journal of Toxicology. Clinical Toxicology
Y KamijoT Ohwada

Abstract

A 23-year-old male pharmacist ingested 1040 mg arsenic trioxide (788 mg trivalent arsenic, 13 mg/kg). After 7 asymptomatic hours, frequent vomiting and diarrhea occurred. Fearing death from shock, he drank 5 L of water over 5 hours. When he was brought to our hospital with chief complaint of constricted vision about 20 hours after ingestion, the major abdominal symptoms had already subsided. Despite a lethal plasma arsenic on admission, all toxic symptoms including hepatic dysfunction, erythematous dermal eruption, and peripheral neuropathy improved during his hospital stay with no treatment except for dimercaptopropanol.

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Jun 9, 2005·Forensic Science International : Synergy·Teresa Lech, Franciszek Trela
Jan 19, 2008·Leukemia & Lymphoma·Jean-Christophe TheryHervé Tilly
Aug 27, 2009·Critical Care : the Official Journal of the Critical Care Forum·Cédric DaubinPierre Charbonneau
Feb 9, 2011·Human & Experimental Toxicology·Esmaeil FarzanehMohammadali Emamhadi
Jul 5, 2005·Pediatrics·Melisa W LaiMichele Burns Ewald

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