PMID: 8970486Dec 1, 1996Paper

Survival after peptic ulcer perforation: a time trend analysis

Journal of Clinical Epidemiology
C SvanesO Søreide

Abstract

The survival of 1098 patients with ulcer perforation in Norway during the period 1952-1990 was compared with expected survival. Cox regression models incorporating population mortality rates, were used to analyse effects of sex, age, year of birth, and year at risk on excess mortality. Survival was lower in patients than in the general population through a follow-up period of 38 years. Relative survival was lower in women as compared to men, due to more delayed treatment. Long-term survival was lower after praepyloric perforations than after the other perforation types. Relative survival was higher in patients treated 1952-1970 than in those treated more recently. However, adjustment for year of birth revealed a decline in short-term mortality with calendar time, which is in accordance with improved management during the study period. Relative mortality, particularly long-term mortality, was higher in younger birth cohorts, suggesting a shift towards more serious etiologies.

References

Feb 1, 1991·The British Journal of Surgery·G LundegårdhU B Krusemo
Nov 1, 1989·World Journal of Surgery·S Ditlevsen
Sep 1, 1984·International Journal of Epidemiology·G N StemmermannG A Glober
Aug 26, 1982·The New England Journal of Medicine·A H RossW P Small
Nov 1, 1994·Scandinavian Journal of Gastroenterology·M Rørbaek-MadsenP Wara
Sep 3, 1994·BMJ : British Medical Journal·K W ClarkeJ R Hampton
Sep 3, 1994·BMJ : British Medical Journal·P WilkinsonA D Timmis
Feb 1, 1994·Digestive Diseases and Sciences·G LundegårdhH O Adami

❮ Previous
Next ❯

Citations

Jul 1, 2010·Irish Journal of Medical Science·J O LarkinP W Eustace
Nov 26, 1999·Journal of Gastroenterology and Hepatology·J M DugganL J Melton
Mar 23, 2007·Journal of Gastroenterology and Hepatology·Belma KocerOmer Cengiz
Aug 1, 1997·Gut·C SvanesO Søoreide
Jun 27, 2007·Journal of Pediatric Gastroenterology and Nutrition·Man-Chin HuaChih-Cheng Luo
Jul 8, 1998·Chronobiology International·C SvanesH Sørbye
Jul 22, 1998·Statistics in Medicine·S A LieC Svanes

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.