Survival After Secondary Prevention Implantable Cardioverter-Defibrillator Placement: An Analysis From the NCDR ICD Registry

JACC. Clinical Electrophysiology
David F KatzFrederick A Masoudi

Abstract

This study sought to define the characteristics and risks of death of patients receiving a physician-designated secondary prevention implantable cardioverter-defibrillator (ICD) in contemporary clinical practice. Data on utilization and outcomes of ICDs for the secondary prevention of sudden cardiac death (SCD) are limited. Patients enrolled in the National Cardiovascular Data Registry's (NCDR) ICD Registry from 2006 to 2009 with a physician-designated secondary prevention indication for ICD implantation were identified and linked to the Social Security Death Master File. Those patients with a history either of tachycardic arrest or sustained ventricular tachycardia (SCD/VT) or of syncope without SCD/VT were included. Kaplan-Meier survival analysis was used to assess mortality. Cox proportional hazards survival modeling was used to assess the risk of death in these groups, adjusting for patient characteristics. In the study cohort of 46,685 patients (mean age 66 ± 14 years, 73.5% male, 85% white), 78% had SCD/VT and 22% had syncope. Overall mortality was 10.4% at 1 year and 16.4% at 2 years. Compared with patients having SCD/VT, the adjusted hazard of death at 1 year was lower in the patients having syncope (hazard ratio: 0.89;...Continue Reading

References

Dec 31, 1997·The New England Journal of Medicine·UNKNOWN Antiarrhythmics versus Implantable Defibrillators (AVID) Investigators
Mar 22, 2002·The New England Journal of Medicine·Arthur J MossUNKNOWN Multicenter Automatic Defibrillator Implantation Trial II Investigators
Jun 27, 2003·The New England Journal of Medicine·T Jared BunchDouglas L Packer
Jan 22, 2005·The New England Journal of Medicine·Gust H BardyUNKNOWN Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators
Jan 7, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Guido H van WelsenesMartin J Schalij
Sep 25, 2012·Journal of the American College of Cardiology·John C MessengerUNKNOWN NCDR Science and Quality Oversight Committee Data Quality Workgroup
Jan 3, 2013·JAMA : the Journal of the American Medical Association·Sana M Al-KhatibArthur J Moss
Feb 14, 2013·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Mark S KremersJohn Rumsfeld
Jul 20, 2014·Circulation. Arrhythmia and Electrophysiology·Paul L HessSana M Al-Khatib
May 6, 2015·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Morten SchmidtHenrik Toft Sørensen

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