Survival analysis of colorectal cancer patients in a Thai hospital-based cancer registry

Expert Review of Gastroenterology & Hepatology
Kankamon KittrongsiriUsa Chaikledkaew

Abstract

Background: The study aimed to assess the overall and stage-specific colorectal cancer (CRC) survival and to identify the prognostic factors for survival among Thai patients.Research design and methods: The retrospective data of CRC patients from a university hospital-based cancer registry from 2001 to 2014 were used to estimate five-year overall survival (OS). Kaplan-Meier method and log-rank tests were used to assess the differences in five-year OS by age at diagnosis, diagnostic period, tumor site, stage at diagnosis and treatment modalities. A multivariate Cox's proportional hazard model was used to identify independent prognostic factors for the OS.Results: A total of 1,507 (48%) colon and 1,648 (52%) rectal cancer patients were included. Five-year OS for CRC patients was 44%. It differed significantly by stage, age group, and treatment received. Stage at diagnosis, age group, diagnostic period, receiving surgical and chemotherapy treatments were prognostic factors for OS.Conclusions: An increasing trend in the number of CRC patients mostly at stage III and IV was found. Our results emphasized that an improvement in CRC survival could be achieved through the adoption of advanced cancer therapies, as well as improved access...Continue Reading

References

Mar 23, 2004·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M G ValsecchiUNKNOWN Monza's International School of Paediatric Hematology-Oncology
Nov 3, 2004·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M MalvezziC La Vecchia
Dec 17, 2009·The Lancet Oncology·Rengaswamy SankaranarayananNasser Al-Hamdan
Dec 17, 2009·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Liliane ChatenoudCarlo La Vecchia
Mar 27, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·UNKNOWN CanTreat International
Nov 22, 2011·Acta Oncologica·Kaire InnosTiiu Aareleid
Dec 14, 2011·Archives of Internal Medicine·Y Nancy YouJanice N Cormier
Jan 13, 2012·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·John F ScogginsScott D Ramsey
May 25, 2012·International Journal of Cancer. Journal International Du Cancer·Sarah WaltersMichel P Coleman
Jul 20, 2012·Diseases of the Colon and Rectum·Sushmita PathyRengaswamy Sankaranarayanan
Jan 11, 2013·Japanese Journal of Clinical Oncology·Melissa C C Teo, Khee Chee Soo
Sep 12, 2013·BMJ Open·Claudia AllemaniMichel P Coleman
Nov 19, 2013·Current Opinion in Gastroenterology·Victoria Gómez, Michael B Wallace
Sep 16, 2014·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayFreddie Bray
Oct 21, 2014·Expert Review of Pharmacoeconomics & Outcomes Research·Panattharin LerdkiattikornYot Teerawattananon
Nov 7, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Nattapoom SermsriSurasak Sangkhathat
Nov 23, 2016·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Rachel K ParsonageRichard D Neal
Aug 16, 2017·World Journal of Gastroenterology : WJG·Fábio Guilherme Campos
Aug 19, 2017·Endoscopic Ultrasound·UNKNOWN Chinese Thoracic Society, UNKNOWN Chinese Alliance against Lung Cancer

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