Abstract
Haemophiliac treatment in less developed countries is limited to locally prepared fresh frozen plasma, cryoprecipitate, cryo-removed plasma and lyophilized products as replacement therapy. Factor concentrate is seldom used because of the high price. The present study reports the survival analysis of 164 patients comprising 138 haemophilia A and 26 haemophilia B cases from 134 families registered at the International Haemophilia Training Centre-Bangkok, Faculty of Medicine, Ramathibodi Hospital, Mahidol University from 1971 to 2000. The duration of follow-up ranged from 1 to 27 years and 8 months with a median of 9 years and 1 month. They received treatment on demand of bleedings, and 85 patients received additional home treatment for early bleedings. The proportion of death was 15.2%. The Kaplan-Meier survival curves revealed the median (95% CI) survival time of patients with severe and moderate degrees of 35 years and 6 months (21.4-49.7), and 38 years and 1 month (28.8-47.3), respectively. To compare the progressive achievement of haemophilia care services, the treatment period was divided into three decades: 1971-1980, 1981-1990 and 1991-2000. The patients with unaided proper walking increased from 62.8% in the first decade ...Continue Reading
References
Dec 1, 1990·Journal of Internal Medicine·F R RosendaalE Briët
Jan 1, 1989·British Journal of Haematology·F R RosendaalE Briët
Apr 1, 1985·British Journal of Haematology·S A Larsson
Jan 1, 1996·Vox Sanguinis·A ChuansumritP Hathirat
May 3, 2000·Haemophilia : the Official Journal of the World Federation of Hemophilia·B L Evatt, L Robillard
Apr 3, 2001·American Journal of Hematology·T L ChorbaB L Evatt
Citations
Jan 22, 2005·Seminars in Hematology·Christine A Lee, Rezan Abdul-Kadir
Aug 1, 2007·Journal of Thrombosis and Haemostasis : JTH·P M Mannucci
Feb 8, 2006·Journal of Thrombosis and Haemostasis : JTH·C Mejia-CarvajalL A Valentino
Jun 29, 2010·Haemophilia : the Official Journal of the World Federation of Hemophilia·R WuJ Zhang
Mar 19, 2016·Haemophilia : the Official Journal of the World Federation of Hemophilia·S P VermaK T Harichandra Kumar
Nov 13, 2009·Haemophilia : the Official Journal of the World Federation of Hemophilia·A L Dunn
Sep 12, 2006·Thrombosis Research·Irina BakaltchevaHelen Ogbu
Jun 30, 2016·Haemophilia : the Official Journal of the World Federation of Hemophilia·A ChuansumritP Wongwerawattanakoon
Apr 5, 2017·Journal of Thrombosis and Haemostasis : JTH·J I LoomansK Fijnvandraat
Jun 29, 2017·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Hassan MansouritorghabehMaryam Behboudi
Feb 22, 2018·Haemophilia : the Official Journal of the World Federation of Hemophilia·S DunkleyUNKNOWN Asia-Pacific Haemophilia Working Group (APHWG)
May 20, 2020·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Tanushree SahooDeepak Bansal
Oct 1, 2021·Haemophilia : the Official Journal of the World Federation of Hemophilia·Arafat Ul AlamHaowei Linda Sun