Survival analysis of revised 2013 FIGO staging classification of epithelial ovarian cancer and comparison with previous FIGO staging classification

Obstetrics & Gynecology Science
E Sun PaikByoung-Gie Kim

Abstract

To analyze the prognostic role of revised version of International Federation of Gynecology and Obstetrics (FIGO) stage (2013) in epithelial ovarian cancer and compare with previous version staging classification. We retrospectively enrolled patients with epithelial ovarian cancer treated at Samsung Medical Center from 2002 to 2012. We reclassified the patients based on the revised FIGO staging classification. Eight hundred seventy-eight patients were enrolled (stage I, 22.8%; stage II, 10.4%; stage III, 56.2%; stage IV, 10.7%). Previous stage IC (98, 11.1%) was subdivided into IC1 (9, 1.0%), IC2 (57, 6.4%), and IC3 (32, 4.1%). In addition, previous stage IV (94, 1.7%) was categorized into IVA (37, 4.2%) and IVB (57, 6.5%) in new staging classification. Stage IIC (66, 7.5%) has been eliminated and integrated into IIA (36, 4.1%) and IIB (55, 6.2%) in revised classification. Revised FIGO stage IC3 had significant prognostic impact on PFS (hazard ratio [HR], 3.840; 95% confidence interval [CI], 1.361 to 10.83; P=0.011) and revised FIGO stage IIIC appears to be an independent, significant poor prognostic factor for PFS (HR, 2.541; 95% CI, 1.242 to 5.200; P=0.011) but not in the case of previous version of FIGO stage IIIC (HR, 1.070...Continue Reading

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Citations

Jun 24, 2016·Gynecologic Oncology·Beyhan AtasevenAndreas du Bois
Nov 2, 2016·Cancer Biomarkers : Section a of Disease Markers·E Sun PaikDuk-Soo Bae
Jan 13, 2018·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Parvin TajikGemma G Kenter
Mar 5, 2016·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Mikkel RosendahlBerit Jul Mosgaard
May 21, 2016·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Tayfun ToptasTayup Simsek
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Apr 11, 2018·Expert Review of Anticancer Therapy·Antoine EliesClaire Bonneau
Sep 21, 2017·Oncology Letters·Monika Englert-GolonStefan Sajdak
May 11, 2019·Journal of Gynecologic Oncology·E Sun PaikSung Wook Seo
Sep 1, 2016·Diagnostic Cytopathology·Jefree J Schulte, Ricardo R Lastra
Dec 3, 2016·Clinical and Translational Medicine·Marek MaleckiXenia Tombokan
Feb 21, 2021·Journal of Vascular and Interventional Radiology : JVIR·Frank YuanSteven S Raman
Mar 7, 2021·International Journal of Environmental Research and Public Health·Agnieszka HoralaZenon J Kokot
Aug 29, 2021·Pharmaceuticals·Dagmara PietkiewiczJan Matysiak

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Methods Mentioned

BETA
biopsies
imaging techniques
dissection
X-ray

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