Survival and DNA degradation in anhydrobiotic tardigrades

The Journal of Experimental Biology
Lorena RebecchiRoberto Guidetti

Abstract

Anhydrobiosis is a highly stable state of suspended animation in an organism due to its desiccation, which is followed by recovery after rehydration. Changes occurring during drying could damage molecules, including DNA. Using the anhydrobiotic tardigrade Paramacrobiotus richtersi as a model organism, we have evaluated the effects of environmental factors, such as temperature and air humidity level (RH), on the survival of desiccated animals and on the degradation of their DNA. Tardigrades naturally desiccated in leaf litter and tardigrades experimentally desiccated on blotting paper were considered. Replicates were kept at 37 degrees C and at different levels of RH for 21 days. RH values and temperature, as well as time of exposure to these environmental factors, have a negative effect on tardigrade survival and on the time required by animals to recover active life after desiccation. DNA damages (revealed as single strand breaks) occurred only in desiccated tardigrades kept for a long time at high RH values. These results indicate that during the anhydrobiotic state, damages take place and accumulate with time. Two hypotheses can be formulated to explain the results: (i) oxidative damages occur in desiccated specimens of P. r...Continue Reading

References

Dec 1, 1994·Microbiological Reviews·M Potts
Sep 2, 1999·Trends in Microbiology·J R BattistaM J Park
Apr 1, 2000·Applied and Environmental Microbiology·D BilliR Ocampo-Friedmann
Apr 6, 2001·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·J S Clegg
Feb 16, 2002·Cryobiology·A E OliverJ H Crowe
Feb 28, 2002·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Willem F WolkersJohn H Crowe
Oct 17, 2003·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·A Tunnacliffe, J Lapinski
Nov 25, 2003·Cell Stress & Chaperones·Elenilda de Jesus PereiraElis Cristina Araujo Eleutherio
Jun 25, 2004·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Robin Holliday
Aug 18, 2004·The International Journal of Biochemistry & Cell Biology·Juan Du, Janusz M Gebicki
Dec 22, 2005·International Journal of Radiation Biology·K Ingemar JönssonJesper Torudd
Apr 4, 2006·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·M B FrançaE C A Eleutherio
Apr 20, 2006·The Journal of Experimental Biology·Peter Alpert
Jun 16, 2006·Mutagenesis·Sherif F El-Khamisy, Keith W Caldecott
Aug 1, 2006·Biochemical and Biophysical Research Communications·Takahiro KikawadaTakashi Okuda
Dec 21, 2006·International Journal of Radiation Biology·Daiki D HorikawaMikinori Kuwabara
Oct 30, 2007·Astrobiology·K Ingemar Jönsson
Mar 26, 2008·Proceedings of the National Academy of Sciences of the United States of America·Minoru SakuraiTakashi Okuda
Mar 26, 2008·Proceedings of the National Academy of Sciences of the United States of America·Eugene Gladyshev, Matthew Meselson
Sep 13, 2008·Current Biology : CB·K Ingemar JönssonPetra Rettberg
Apr 14, 2009·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Simon NeumannRalph O Schill
Nov 1, 2005·Integrative and Comparative Biology·Peter Alpert
Nov 1, 2005·Integrative and Comparative Biology·Kshamata GoyalAlan Tunnacliffe
Nov 1, 2005·Integrative and Comparative Biology·John H CroweFern Tablin

❮ Previous
Next ❯

Citations

Aug 29, 2012·Astrobiology·Diego FontanetoMartin Westberg
Nov 26, 2015·Proceedings of the National Academy of Sciences of the United States of America·Thomas C BoothbyBob Goldstein
Mar 29, 2011·Journal of Insect Physiology·Weronika WełniczMarcus Frohme
Mar 25, 2011·Zoology : Analysis of Complex Systems, ZACS·Roberto GuidettiLorena Rebecchi
Mar 16, 2011·Journal of Insect Physiology·Roberto GuidettiLorena Rebecchi
Mar 9, 2010·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Angela M RizzoLorena Rebecchi
Nov 25, 2011·DNA Repair·Michael J Daly
Jun 15, 2011·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Steffen HengherrJ S Clegg
Apr 25, 2018·PLoS Biology·Reuben W NowellTimothy G Barraclough
Oct 22, 2016·Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life·Erdmann Weronika, Kaczmarek Łukasz
Apr 10, 2019·Movement Ecology·Diego Fontaneto
Aug 2, 2018·Scientific Reports·Thomas L Sørensen-HygumNadja Møbjerg
Feb 11, 2020·Frontiers in Plant Science·Tran Le Cong Huyen Bao PhanPatrick Van Dijck
Nov 17, 2020·Frontiers in Physiology·Jonathan D HibshmanBob Goldstein

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved