Survival and functional status 20 or more years after first stroke: the Framingham Study

Stroke; a Journal of Cerebral Circulation
G E GreshamR B D'Agostino

Abstract

We examined the 20-or-more-year survival and functional levels of 148 stroke survivors and 148 age- and sex-matched control subjects from the Framingham Study Cohort, whom we originally studied in 1972-1974 to ascertain the survival and disability status of stroke survivors compared with that of controls. This long-term evaluation was done with use of data from the 1993-1995 Framingham Study Cohort Examination 23 on the 10 stroke survivors and 20 control subjects still living to identify and compare the host characteristics and functional status of each group. The survival curves for both stroke survivors and controls were derived from the ongoing Framingham Study database. Twenty-plus-year stroke survivors experienced a greater mortality than age- and sex-matched controls (92.5% and 81%, respectively). The slopes of the two survival curves were essentially the same. Functional status (eg, walking and independence in activities of daily living) of stroke survivors, however, compared very favorably with that of the control subjects. Stroke survivors were more likely to be female and to have a number of comorbidities, including elevated blood pressures, greater use of medications, less use of alcohol, and less depressive symptomo...Continue Reading

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Citations

May 3, 2003·Journal of Clinical Epidemiology·Gosse de JongJan Lodder
Oct 22, 2004·The Journal of Cardiovascular Nursing·Margaret Kelly-Hayes
Jun 1, 2006·Journal of Neurology, Neurosurgery, and Psychiatry·I van WijkUNKNOWN LiLAC Study Group
Feb 13, 2009·Stroke; a Journal of Cerebral Circulation·Rodica E PetreaPhilip A Wolf
Jul 25, 2009·Stroke; a Journal of Cerebral Circulation·Afshin A DivaniAndreas R Luft
Aug 14, 2009·Expert Review of Cardiovascular Therapy·Christoph GlobasAndreas R Luft
Mar 1, 2007·Annals of Neurology·Marieke van OijenMonique M B Breteler
Oct 2, 2007·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Morten Nonboe AndersenTom Skyhøj Olsen
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Oct 23, 2010·Neurología : publicación oficial de la Sociedad Española de Neurología·A Gil Núñez
Jan 18, 2006·Acta Neurologica Scandinavica·Q ShenM Karr
Jan 2, 2001·Angiology·T J TegosA N Nicolaides
Nov 1, 2018·The International Journal of Cardiovascular Imaging·Andrea SonaglioniMichele Lombardo
Aug 31, 2018·International Journal of Stroke : Official Journal of the International Stroke Society·Ravinder-Jeet SinghMichael D Hill

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