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Survival and Prognostic Factors in C9orf72 Repeat Expansion Carriers: A Systematic Review and Meta-analysis

JAMA Neurology

Nov 18, 2019

Stella Andrea GlasmacherSuvankar Pal

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Abstract

The c9orf72 repeat expansion (c9 or c9orf72RE) confers a survival disadvantage in amyotrophic lateral sclerosis (ALS); its effect on prognosis in frontotemporal dementia (FTD) remains uncertain. Data on prognostic factors in c9orf72RE disorders could inform patient care, genetic counsel...read more

Mentioned in this Paper

Amyotrophic Lateral Sclerosis
Mental Disorders
Cell Growth
Chromosomes, Human, Pair 9
Clinical Trials
Patient Care
Genetic Counseling
Motor Neurons
Regression Analysis
Protein TDP-43
17
1
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Survival and Prognostic Factors in C9orf72 Repeat Expansion Carriers: A Systematic Review and Meta-analysis

JAMA Neurology

Nov 18, 2019

Stella Andrea GlasmacherSuvankar Pal

PMID: 31738367

DOI: 10.1001/jamaneurol.2019.3924

Abstract

The c9orf72 repeat expansion (c9 or c9orf72RE) confers a survival disadvantage in amyotrophic lateral sclerosis (ALS); its effect on prognosis in frontotemporal dementia (FTD) remains uncertain. Data on prognostic factors in c9orf72RE disorders could inform patient care, genetic counsel...read more

Mentioned in this Paper

Amyotrophic Lateral Sclerosis
Mental Disorders
Cell Growth
Chromosomes, Human, Pair 9
Clinical Trials
17
1

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