Survival and the development of azotemia after treatment of hyperthyroid cats

Journal of Veterinary Internal Medicine
T L WilliamsHarriet Syme

Abstract

Hyperthyroidism complicates the diagnosis of chronic kidney disease (CKD) as it increases glomerular filtration rate. No practical and reliable means for identifying those cats that will develop azotemia after treatment for hyperthyroidism has been identified. Hyperthyroidism is associated with proteinuria. Proteinuria has been correlated with decreased survival of cats with CKD and with progression of CKD. Proteinuria and other clinical parameters measured at diagnosis of hyperthyroidism will be associated with the development of azotemia and survival time. Three hundred client owned hyperthyroid cats treated in first opinion practice. Retrospective, cohort study relating clinical parameters in hyperthyroid cats at diagnosis to the development of azotemia within 240 days of diagnosis and survival time (all cause mortality). Multivariable logistic regression analysis was used to identify factors that were predictive of the development of azotemia. Multivariable Cox regression analysis was used to identify factors associated with survival. Three hundred cats were eligible for survival analysis and 216 cats for analysis of factors associated with the development of azotemia. The median survival time was 417 days, and 15.3% (41/26...Continue Reading

References

May 1, 1997·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·W H AdamsC A Grove
May 29, 2000·Journal of the American Animal Hospital Association·T J BeckerR F Nachreiner
Feb 13, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A Benigni, G Remuzzi
Feb 24, 2001·Journal of Veterinary Internal Medicine·M R SlaterK Rogers
Jul 3, 2002·Journal of the American Veterinary Medical Association·Harriet M SymeJonathan Elliott
Nov 5, 2003·American Journal of Veterinary Research·Anna M FirshmanCarrie J Finno
Apr 6, 2005·Clinical Endocrinology·Jan G den HollanderArie Berghout
Feb 16, 2006·Journal of the American Veterinary Medical Association·Rowan J MilnerMichael Schaer
Jun 8, 2007·Journal of Veterinary Internal Medicine·Rosanne E JepsonHarriet M Syme
Dec 19, 2007·Journal of Feline Medicine and Surgery·Melissa R RienscheDavid J Schaeffer
Jan 10, 2009·General and Comparative Endocrinology·Ingrid van Hoek, Sylvie Daminet
Jun 6, 2009·Journal of Veterinary Internal Medicine·K GommerenS Daminet
Jul 2, 2009·Journal of Veterinary Internal Medicine·R E JepsonJ Elliott

❮ Previous
Next ❯

Citations

Jun 26, 2013·The Journal of Small Animal Practice·T L WilliamsH M Syme
Oct 27, 2016·The Journal of Small Animal Practice·R E JepsonP B Munroe
Mar 2, 2017·Journal of Feline Medicine and Surgery·Samantha S TaylorBrian A Scansen
May 5, 2016·Journal of Feline Medicine and Surgery·Hazel C CarneyA Renee Rucinsky
Mar 12, 2016·Journal of Feline Medicine and Surgery·Lucy KopecnyAndrea M Harvey
Mar 10, 2015·Journal of Feline Medicine and Surgery·Heather H VaskeGregory F Grauer
Sep 6, 2013·Journal of Feline Medicine and Surgery·Brice S Reynolds, Hervé P Lefebvre
Sep 23, 2014·Journal of Feline Medicine and Surgery·Jordi PuigMayank Seth
Jan 16, 2014·Journal of Feline Medicine and Surgery·Paul HiggsAngie Hibbert
Jul 13, 2017·Journal of Feline Medicine and Surgery·Marie VagneyPauline de Fornel-Thibaud
Jan 12, 2019·Journal of Veterinary Internal Medicine·Eva BuresovaSylvie Daminet
Feb 14, 2019·Journal of Veterinary Internal Medicine·Heather L CoveyHarriet M Syme
Apr 27, 2019·The Veterinary Record·Megan ConroyJonathan Elliott
Jul 23, 2019·The Journal of Small Animal Practice·N C FinchA Hibbert
Jan 1, 2014·The Journal of Small Animal Practice·S DaminetG Williams
Nov 16, 2017·Journal of Veterinary Pharmacology and Therapeutics·J E HareW E Lloyd
Nov 22, 2018·Journal of Feline Medicine and Surgery·S Karlyn BlandDorothee Bienzle
Jul 11, 2019·Journal of Feline Medicine and Surgery·Stefanie M DeMonacoStephen Werre
May 8, 2016·Journal of Veterinary Internal Medicine·T L WilliamsJ Archer
Mar 23, 2013·Journal of Veterinary Internal Medicine·T L WilliamsH M Syme
Aug 6, 2021·Journal of Veterinary Internal Medicine·Mark E Peterson, Mark Rishniw
Nov 4, 2021·Journal of Feline Medicine and Surgery·Joyce Ly Chow, Joanna White

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.