Survival benefit of non-curative gastrectomy for gastric cancer patients with synchronous distant metastasis.

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Chen LiYan Zheng Lin

Abstract

The prognosis for gastric cancer patients with distant metastasis is very poor. The purpose of this study was to evaluate the survival benefit of non-curative gastrectomy for gastric cancer patients with synchronous distant metastasis. From 1992 to 2002, 253 gastric cancer patients with synchronous distant metastasis underwent surgery at the Department of Surgery, Ruijin Hospital, China. The clinicopathological characteristics and survival were compared between resection and non-resection groups. The 5-year survival rate was 6.5% for patients in resection group and 0% for patients in non-resection group (P < 0.001). Multivariate analysis showed that liver metastasis, peritoneal dissemination, and non-resection were significantly associated with poor prognosis in gastric cancer patients with distant metastasis. The survival difference between resection and non-resection groups was only observed in patients with single peritoneal dissemination (P < 0.001), but were not in patients with single liver metastasis (P = 0.428), distant nodes involvement (P = 0.490) and multiple metastatic sites (P = 0.192), respectively. Our results suggests that there were no survival benefit from non-curative gastrectomy for patients with single live...Continue Reading

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Citations

Sep 24, 2015·International Journal of Oncology·Xiaoping RanWeiqun Zeng
Aug 12, 2015·Nature Reviews. Clinical Oncology·Sri G ThrumurthyWilliam Allum
Mar 23, 2017·The Surgical Clinics of North America·Eleftherios A Makris, George A Poultsides
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Jul 18, 2015·World Journal of Gastroenterology : WJG·Daniele MarrelliFranco Roviello

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