Survival during renal replacement therapy for diabetic end-stage renal disease in Pima Indians

Diabetes Care
R G NelsonP H Bennett

Abstract

To examine survival in Pima Indians receiving renal replacement therapy for end-stage renal disease attributed to NIDDM. Vital status through 1994 was determined for 136 diabetic Pima Indians from the Gila River Indian Community who began renal replacement therapy between 1973 and 1990. Median survival from the onset of renal replacement therapy was 39 months (95% Ci, 31-54), 31 months (95% Ci, 11-48) in those who began treatment between 1973 and 1981, and 44 months (95% Ci, 32-56) in those who began treatment between 1982 and 1990 (P = 0.020). During these periods, mean age at onset of treatment increased from 53.3 to 56.1 years (P = 0.166), and mean duration of diabetes at the onset of treatment increased from 16.5 to 20.2 years (P = 0.003). After adjustment for sex, duration of diabetes, initial dialysis type, and kidney transplantation by an age-stratified proportional-hazards analysis, the death rate after starting renal replacement therapy in the second half of the study was 0.54 times (95% CI, 0.33-0.88) that in the first half. If this analysis was restricted to those who survived at least 90 days of therapy, the difference between the time periods was diminished (death rate ratio = 0.76; 95% CI, 0.43-1.32). Survival in ...Continue Reading

Citations

Apr 24, 2014·American Journal of Public Health·Nilka Ríos BurrowsPaul W Eggers
Sep 5, 2008·Diabetes Research and Clinical Practice·Mariam NaqshbandiFred Antwi-Nsiah
Feb 13, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Christine A StidleyPhilip G Zager
Apr 29, 2004·Diabetes Care·Bessie A YoungGayle Reiber
Jul 7, 1999·Circulation·M L SieversR G Nelson
Jul 30, 2011·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Suma Prakash

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