Survival following Pulmonary Metastasectomy for Sarcoma

The Thoracic and Cardiovascular Surgeon
Lawrence OkirorManinder Kalkat

Abstract

The aim of this study is to report the overall survival after pulmonary metastasectomy in patients with metastatic sarcoma and prognostic factors for survival. This is a retrospective observational study of consecutive patients having pulmonary metastasectomy for sarcoma over a 5-year period. Survival was calculated by Kaplan-Meier method. Between August 2007 and January 2014, a total of 80 pulmonary metastasectomies were performed on 66 patients with metastatic sarcoma. There were no postoperative in-hospital deaths. The median age was 51 years (range, 16-79) and 39 (59%) patients were male. Fourteen patients had bilateral lung operations and surgical access was by video-assisted thoracoscopic surgery in 48 (73%) cases. The median number of metastases resected was 3 (range, 1-9). The median disease-free interval was 25 months (range, 0-156). Median overall survival was 25.5 months (range, 1-60). At follow-up, 19 patients (29%) were dead with a median follow-up of 31 months (range, 1-60). Recurrence of metastases significantly affected survival: median of 25.5 months (95% confidence interval [CI], 17.7-33.4) versus 48.4 months (95% CI, 42.5-54.4) in patients with no recurrent metastases (p = 0.004). There was no significant dif...Continue Reading

Citations

Dec 29, 2015·Journal of Pediatric Surgery·Anna RaciborskaWojciech Wożniak
Aug 5, 2017·BMJ Case Reports·Nasir AliBilal Mazhar Qureshi
Feb 12, 2020·Cost Effectiveness and Resource Allocation : C/E·Susie BaeSusan Neuhaus
Aug 17, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Fabio TirottaL Max Almond
Sep 14, 2021·Interactive Cardiovascular and Thoracic Surgery·Charles A GushoMarta Batus

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