PMID: 8581391Oct 1, 1995Paper

Survival following radiotherapy for post-surgical locoregional recurrence of non-small cell lung cancer

Lung Cancer : Journal of the International Association for the Study of Lung Cancer
J LeungC Laidlaw

Abstract

Long term survival [> 3 years] has been documented in patients treated with radiotherapy for bronchial stump recurrence following surgery for non-small cell lung cancer [NSCLC]. In this retrospective review of 45 patients with locoregional recurrence of NSCLC we measured survival following radiotherapy according to site of recurrence [bronchial stump or elsewhere] and treatment intent. Estimated median survival for all 45 patients from presentation was 10 months. Ten patients whose disease was confined to the bronchial stump had an estimated median survival of 15 months compared with 9 months for patients with recurrence elsewhere [P = 0.4]. Seventeen patients treated with radical intent [dose > 50 Gy] had an estimated median survival of 16 months, with an estimated 41% alive at two years. The overall survival of patients treated with radical intent is not dissimilar to that of a group of our patients treated similarly with primary radiotherapy for inoperable NSCLC. We conclude that a policy of high dose radiotherapy may be justified in selected patients with recurrent NSCLC.

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Citations

Sep 21, 2002·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Branislav Jeremic, Michael Bamberg
Aug 12, 1998·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Y KagamiA Saito
Apr 27, 1999·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·B JeremicG Radosavljevic-Asic
Apr 22, 2011·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Dong-Soo LeeByung-Oak Choi
Apr 17, 2014·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Jeremy M KilburnJames J Urbanic
Oct 1, 2013·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Jiro OkamiMasahiko Higashiyama
Jun 23, 2009·International Journal of Radiation Oncology, Biology, Physics·Xu-Wei CaiFeng-Ming Kong
Sep 26, 2003·Seminars in Surgical Oncology·Frank B ZimmermannBranislav Jeremic
Jun 5, 2016·Clinical Oncology : a Journal of the Royal College of Radiologists·J ShafiqM B Barton
May 26, 2016·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Matthew C WardKevin L Stephans

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