Survival in daily home hemodialysis and matched thrice-weekly in-center hemodialysis patients.

Journal of the American Society of Nephrology : JASN
Eric D WeinhandlAllan J Collins

Abstract

Frequent hemodialysis improves cardiovascular surrogates and quality-of-life indicators, but its effect on survival remains unclear. We used a matched-cohort design to assess relative mortality in daily home hemodialysis and thrice-weekly in-center hemodialysis patients between 2005 and 2008. We matched 1873 home hemodialysis patients with 9365 in-center patients (i.e., 1:5 ratio) selected from the prevalent population in the US Renal Data System database. Matching variables included first date of follow-up, demographic characteristics, and measures of disease severity. The cumulative incidence of death was 19.2% and 21.7% in the home hemodialysis and in-center patients, respectively. In the intention-to-treat analysis, home hemodialysis associated with a 13% lower risk for all-cause mortality than in-center hemodialysis (hazard ratio [HR], 0.87; 95% confidence interval [95% CI], 0.78-0.97). Cause-specific mortality HRs were 0.92 (95% CI, 0.78-1.09) for cardiovascular disease, 1.13 (95% CI, 0.84-1.53) for infection, 0.63 (95% CI, 0.41-0.95) for cachexia/dialysis withdrawal, 1.06 (95% CI, 0.81-1.37) for other specified cause, and 0.59 (95% CI, 0.44-0.79) for unknown cause. Findings were similar using as-treated analyses. We did ...Continue Reading

References

Jan 7, 2000·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·P L HebertA M McBean
Apr 19, 2002·Journal of the American Society of Nephrology : JASN·Austin G Stack
Oct 17, 2002·American Journal of Nephrology·Mauro B AndréJocemir R Lugon
Oct 2, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Garabed EknoyanRobert Toto
May 7, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ernesto PaolettiGiuseppe Cannella
May 11, 2005·Kidney International. Supplement·Steven G Achinger, Juan Carlos Ayus
Mar 30, 2006·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·Elizabeth A McDade-MontezWilliam J Lawton
Mar 22, 2007·Seminars in Dialysis·Mary Alice Kalpakian, Rajnish Mehrotra
Aug 21, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Rita S SuriJohn T Daugirdas
Aug 19, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Csaba P KovesdyKamyar Kalantar-Zadeh
May 7, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Carl M KjellstrandChristopher R Blagg
Jan 13, 2009·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Bret A NicksMichael T Fitch
Apr 3, 2009·Clinical Journal of the American Society of Nephrology : CJASN·Patrick S ParfreyPatrick Lefebvre
Feb 6, 2010·Journal of the American Society of Nephrology : JASN·Eric D WeinhandlAllan J Collins
May 1, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Thomas J ArnesonAllan J Collins
Aug 3, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Bertrand L JaberUNKNOWN FREEDOM Study Group
Nov 26, 2010·The New England Journal of Medicine·Glenn M ChertowAlan S Kliger
Mar 19, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Bertrand L JaberUNKNOWN FREEDOM Study Group
Jun 3, 2011·JAMA : the Journal of the American Medical Association·John P A Ioannidis, Orestis A Panagiotou

❮ Previous
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Citations

Jul 25, 2012·Nature Reviews. Nephrology·Karthik K TennankoreSimon P Curran
Oct 24, 2012·Nature Reviews. Nephrology·Matthew J DamasiewiczPeter G Kerr
Jan 9, 2013·Nature Reviews. Nephrology·Rajnish Mehrotra, Jonathan Himmelfarb
Jan 10, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Robert P Pauly
Dec 14, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Michael E Schachter, Christopher T Chan
Apr 19, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Charles ChazotMadhukar Misra
Oct 26, 2012·Nephron. Clinical Practice·S M PrabhavalkarA E Courtney
Sep 12, 2013·BMC Nephrology·Karthik K TennankoreChristopher T Chan
Oct 6, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Bessie A YoungUNKNOWN ASN Dialysis Advisory Group
Oct 23, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Chris W McIntyre
Jan 17, 2014·BMC Nephrology·Richard J FluckRobert S Lockridge
Feb 18, 2014·BMC Nephrology·Michael E SchachterChristopher T Chan
Nov 2, 2013·International Urology and Nephrology·Martin AguilarIstvan Mucsi
Oct 30, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Karthik TennankoreChristopher T Chan
Sep 21, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Jeffrey PerlChristopher T Chan
Sep 3, 2013·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Ben WongRobert P Pauly
Dec 18, 2013·Kidney International·Raymond M Hakim, Sharmeela Saha
Mar 19, 2015·Kidney International·Rita S SuriGihad E Nesrallah
Dec 29, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Rebecca Kurnik SeshasaiLaura M Dember
Dec 20, 2015·Philosophy, Ethics, and Humanities in Medicine : PEHM·Giorgina Barbara PiccoliUNKNOWN Working group of the students of the Torino Medical School
Sep 1, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Eric D WeinhandlAllan J Collins
Dec 12, 2012·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Mark R MarshallJoanna L Dunlop
Apr 18, 2015·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Sooraj KuttykrishnanRajnish Mehrotra
Mar 19, 2013·Hemodialysis International·Michael E SchachterChristopher T Chan
Jul 10, 2013·Seminars in Dialysis·Jose A Diaz-BuxoRainer Himmele
Mar 8, 2013·Journal of Renal Care·Warren Pickering
Sep 26, 2012·Seminars in Dialysis·Michelle C LewickiKevan R Polkinghorne
Feb 18, 2014·Seminars in Dialysis·Katherine OsterlundGihad Nesrallah
May 1, 2015·Hemodialysis International·Robert LockridgeCarolyn Van Eps
Dec 23, 2014·Nephrology·Meg J JardineUNKNOWN ACTIVE Dialysis Steering Committee
Jan 9, 2014·Hemodialysis International·Eero HonkanenDeborah Zimmerman
Mar 24, 2016·Canadian Journal of Kidney Health and Disease·Gihad E NesrallahRita S Suri
Nov 13, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Mark R MarshallStephen P McDonald
Aug 25, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Meg Jardine, Vlado Perkovic
Apr 22, 2015·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Hikmet IsmayilovFariz Babayev
Jan 15, 2015·Nursing Research and Practice·C VestmanM Berglund
Dec 20, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Annie-Claire Nadeau-FredetteDavid W Johnson
Dec 3, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Karthik K TennankoreChristopher T Chan
Aug 3, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Eric D WeinhandlAllan J Collins
Jan 9, 2015·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Laura LabriolaMichel Jadoul
Jan 9, 2015·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Panagiotis I Georgianos, Pantelis A Sarafidis
Dec 30, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Panagiotis I Georgianos, Pantelis A Sarafidis
Dec 30, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Laura LabriolaMichel Jadoul
Oct 21, 2016·Journal of the American Geriatrics Society·Miklos Z MolnarKamyar Kalantar-Zadeh

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