PMID: 1182075Mar 1, 1975Paper

Survival in localized nodal and extranodal non-Hodgkin's lymphomata.

The British Journal of Cancer. Supplement
M J PeckhamR J Lukes

Abstract

A retrospective analysis of 133 patients with localized nodal and extranodal non-Hodgkin's lymphomata whose staging investigations included marrow aspirate and lymphography shows that more than 60% remain alive and disease-free 4 years after initial therapy. Further relapses may occur in this group, particularly in the nodular lymphomata, but so far the majority of relapses and three quarters of the deaths from disease have occurred within 2 years of diagnosis. Of the entire group of patients, only 15% showed an unequivocally nodular pattern and a further 25% a partially nodular, partially diffuse pattern. Thus, 60% of patients had diffuse lymphoma but differences were observed depending upon the site of presentation. In the nodal Stages I and II cases, whereas only 4 of 55 patients with supradiaphragmatic disease showed a nodular pattern, 12 of 24 infradiaphragmatic presentations had nodular lymphoma. This difference was reflected in a lower relapse rate in the latter group. Mediastinal involvement was uncommon but carried a grave prognosis. As far as it was possible to judge, extension to adjacent nodal areas as a cause of relapse was not a common problem and, as observed previously, relapse was much commoner to a wide variet...Continue Reading

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.

Related Papers

The British Journal of Cancer. Supplement
G BonadonnaU Veronesi
The British Journal of Cancer. Supplement
P S ScheinV T DeVita
The British Journal of Cancer. Supplement
K BreurJ M Van Turnhout
The British Journal of Cancer. Supplement
L M FullerM P Sullivan
© 2022 Meta ULC. All rights reserved