Survival in pancreatic carcinoma based on tumor size

Pancreas
Banke AgarwalLinus Ho

Abstract

The size of pancreatic tumors that can be diagnosed by preoperative imaging continues to decrease because advances in diagnostic imaging. Several surgical series have suggested that survival is better in tumors 20 mm or smaller (vs tumors >20 mm), but the incremental benefit of diagnosing progressively smaller tumors from 30 mm (currently, the average size of pancreatic tumor at diagnosis) to 20 mm or smaller is not known. We investigated survival and resectability as tumor size increased from 20 mm or smaller to 30 mm or larger. This is a retrospective analysis of consecutive patients with pancreatic cancer, who underwent endoscopic ultrasound-guided fine-needle aspiration at MD Anderson Cancer Center between December 2000 and December 2001. Tumor size was based on the combination of endoscopic ultrasound and computed tomography imaging. The median (+/-SE) for tumors 20 mm or smaller, 21 to 25 mm, 26 to 30 mm and larger than 30 mm was 17.2 +/- 8.2, 12.3 +/- 4.9, 8.5 +/- 3.6, and 7.6 +/- 1.2 months (P = 0.021), respectively. Tumors were resectable in 10 (83%) of 12 tumors 20 mm or smaller, 8 (67%) of 12 tumors 21 to 25 mm, 5 (36%) of 14 of tumors 26 to 30 mm, and 2 (7%) of 27 tumors larger than 30 mm (P < 0.001). A dramatic cha...Continue Reading

References

Jul 1, 1994·Gastrointestinal Endoscopy·M F CatalanoJ Van Dam
Sep 1, 2000·Gastrointestinal Endoscopy·H R MertzS D Leach
Oct 19, 2000·American Journal of Surgery·M BouvetA R Moossa
Feb 22, 2001·Gastrointestinal Endoscopy
Jan 9, 2003·Gastrointestinal Endoscopy·Stephen J RulyakTeresa A Brentnall
Sep 26, 2003·Psychosomatic Medicine·Caroline P CarneyBradley N Doebbeling
Jan 21, 2004·Journal of Gastroenterology and Hepatology·Jee-Eun KimKyoo Wan Choi
Apr 16, 2004·Pancreas·Norio SawabuYoshiharu Motoo
Jun 30, 2004·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Marcia Irene CantoRalph H Hruban
Jan 27, 2005·Gastrointestinal Endoscopy·Douglas G AdlerUNKNOWN ASGE
Aug 9, 2005·Gastroenterology·Suresh T ChariGloria M Petersen
Apr 21, 2007·Pancreas·Diane M SimeoneCraig D Logsdon

❮ Previous
Next ❯

Citations

Jul 13, 2013·Journal of Pharmacokinetics and Pharmacodynamics·Gaurav BajajJeffrey S Barrett
Jan 20, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Naveen B KrishnaBanke Agarwal
Jun 2, 2011·Nature Reviews. Gastroenterology & Hepatology·John S LeedsDavid S Sanders
Jun 2, 2011·Proceedings of the National Academy of Sciences of the United States of America·Stefan EserDieter Saur
Jul 1, 2014·Pancreas·Carolina TorresAna Linares
Oct 8, 2014·The American Journal of Gastroenterology·Satish MunigalaBanke Agarwal
Jan 19, 2016·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Antonella De RosaDhanwant Gomez
Jan 5, 2011·Annales d'endocrinologie·Y M DehayemS Halimi
Aug 17, 2010·International Journal of Radiation Oncology, Biology, Physics·Nils D ArvoldTheodore S Hong
Jan 21, 2014·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Satish MunigalaBanke Agarwal
Aug 15, 2009·Magyar sebészet·Attila Oláh
Feb 9, 2017·The British Journal of Surgery·D AnsariR Andersson
Mar 15, 2018·Annals of Medicine·Carolina Torres, Paul J Grippo
Jun 13, 2018·Pancreas·Willemieke S TummersRutger-Jan Swijnenburg
Sep 28, 2018·International Journal of Cancer. Journal International Du Cancer·Kazufumi HondaRudolf Kaaks
Jan 17, 2019·Molecular Biology and Evolution·Yuezheng ZhangXuemei Lu
Jun 21, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yasunobu YamashitaReiko Ashida
Sep 17, 2017·Oncotarget·Willemieke S TummersRutger-Jan Swijnenburg
Jan 1, 2020·Journal of Clinical Medicine·Chun-Cheng ChiangWey-Ran Lin
Apr 12, 2017·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Yoshinori TakedaHiromichi Ito
Oct 2, 2020·Pancreas·Karolina Elżbieta Kaczor-UrbanowiczYong Kim
Apr 22, 2015·World Journal of Gastroenterology : WJG·Si-Biao SuHai-Xing Jiang
Mar 29, 2020·Cancers·Charlotte Maulat The Bacap Consortium
Jun 19, 2014·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Darragh P O'BrienJohn F Timms
Jan 19, 2021·Journal of Oral and Maxillofacial Pathology : JOMFP·J GowthamiDaffney Mano Doss
Apr 3, 2021·Scientific Reports·Aysha FerdoushiHubert Hondermarck
Apr 13, 2012·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Mitsuyoshi YoshimotoKeiji Wakabayashi
Jul 10, 2021·Radiology. Imaging Cancer·Po-Ting ChenWeichung Wang
Sep 3, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Van Gia TruongHyun Wook Kang
Sep 15, 2021·European Journal of Nuclear Medicine and Molecular Imaging·Weiyu ChenWeibo Cai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved