Survival of neonates with enteroviral myocarditis requiring extracorporeal membrane oxygenation

Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Kate MaddenSatish K Rajagopal

Abstract

Neonates infected with enteroviruses may present with severe myocarditis and medically refractory cardiopulmonary collapse. Extracorporeal membrane oxygenation (ECMO) has been used to support patients in this setting, but its efficacy has not been systematically studied. We sought to review the Extracorporeal Life Support Organization registry to determine survival rates and identify predictors of in hospital mortality for these neonates. Retrospective cohort study using data reported to the Extracorporeal Life Support Organization registry. Multi-institutional data. Patients ≤ 15 days old with enteroviral myocarditis who required ECMO support between 2000 and 2008. None. Twenty-four neonates with enteroviral myocarditis were reported to the Extracorporeal Life Support Organization registry during the study period. The survival to hospital discharge rate was 33% (n = 8). Multisystem organ dysfunction was more common in nonsurvivors than in survivors (75% vs. 0%, p < .01). In particular, nonsurvivors had a higher prevalence of renal dysfunction (50% vs. 0%, p = .02). Nonsurvivors also had a greater number of ECMO-related complications (5 vs. 3.5, p = .03). Cardiopulmonary support with ECMO should be considered for neonates with ...Continue Reading

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Citations

Jun 14, 2013·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·V Ben SivarajanPeter C Laussen
May 23, 2015·Pediatric Annals·Julia C Haston, Terry C Dixon
May 29, 2013·Journal of Paediatrics and Child Health·Luregn J SchlapbachChristian Stocker
Oct 25, 2016·Frontiers in Pediatrics·Matteo Di NardoAntonio Amodeo
Oct 4, 2017·Archives of Disease in Childhood. Fetal and Neonatal Edition·Gerard CortinaWarwick Butt
May 1, 2021·Journal of Clinical Medicine·Priya BhaskarRavi Thiagarajan

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