PMID: 9433999Jan 20, 1998Paper

Survival of patients with congenital diaphragmatic hernia during the ECMO era: an 11-year experience

Journal of Pediatric Surgery
N SsemakulaS J Bond

Abstract

Congenital diaphragmatic hernia (CDH) is associated with significant mortality and morbidity. To evaluate the impact of extracorporeal membrane oxygenation (ECMO) on survival, a review of our experience with CDH patients was initiated. The authors performed a retrospective nonrandomized analysis of 98 consecutive CDH patients who were ECMO candidates, and were symptomatic within the first day of life, and underwent repair between May 1985 and May 1996. The patients were divided into three groups: Group 1 (n = 38) refers to patients who were clinically stable and underwent repair before 48 hours of age and did not need ECMO rescue; Group 2 (n = 29) consists of patients who underwent repair but required ECMO rescue; and Group 3 (n = 31) refers to patients who met ECMO criteria preoperatively and required ECMO for stabilization and later underwent repair on ECMO. The Kaplan-Meier survival graph was used for survival analysis. During the 11-year span, the overall survival rate of all CDH patients was 72% (71 of 98). The survival rate of patients who did not require ECMO support was 92% (35 of 38), whereas patients who required ECMO after repair had a 72% (21 of 29) survival rate. These were compared with a 48% (15 of 31) survival r...Continue Reading

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Citations

Oct 12, 2000·Indian Journal of Pediatrics·M AroraT R Prasad
Nov 2, 2007·Pediatric Surgery International·Geraldine Yin Taeng NgSandra Adamson Calvert
Oct 3, 2002·American Journal of Respiratory and Critical Care Medicine·Desmond Bohn
Mar 22, 2005·American Journal of Respiratory and Critical Care Medicine·Scott M NelsonRobert Hume
Aug 28, 2009·Journal of Perinatology : Official Journal of the California Perinatal Association·R ShimonoH Takamatsu
Feb 12, 2010·Journal of Perinatology : Official Journal of the California Perinatal Association·S B HoffmanB L Short
Sep 9, 2015·Pediatric Pulmonology·Montaha M Al-IedeDominic A Fitzgerald
Nov 18, 2004·Journal of Pediatric Surgery·Christopher E ColbyUNKNOWN Congenital Diaphragmatic Hernia Study Group
Jun 9, 2015·Seminars in Pediatric Surgery·Dakshesh H Parikh, Shree Vishna Rasiah
Jan 29, 2010·Journal of Pediatric Surgery·Tim JancelewiczKerilyn Nobuhara
Mar 17, 2005·Seminars in Pediatric Surgery·Karen P Harrington, Alan P Goldman
Jun 16, 2009·Journal of Pediatric Surgery·Jason C FisherMarc S Arkovitz
Apr 12, 2017·Birth Defects Research·Cynthia F HintonStuart K Shapira
Apr 16, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E GarneUNKNOWN Euroscan Study Group
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Mar 17, 2007·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C JeantyR Romero
Feb 13, 2004·Journal of Perinatology : Official Journal of the California Perinatal Association·Matthew SebaldIstvan Seri
Nov 26, 2013·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Parthak ProdhanXinyu Tang
Sep 6, 2000·Pediatric Pulmonology·M W Beresford, N J Shaw
Jul 7, 2017·Pulmonary Circulation·Thomas J Kulik, Eric D Austin
Jul 19, 2021·Journal of Pediatric Surgery·Claire D GerallVincent P Duron

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