Survival Outcomes After Intracranial Hemorrhage in Liver Disease

Operative Neurosurgery
Carlito LagmanIsaac Yang

Abstract

Survival outcomes for patients with liver disease who suffer an intracranial hemorrhage (ICH) have not been thoroughly investigated. To understand survival outcomes for 3 groups: (1) patients with an admission diagnosis of liver disease (end-stage liver disease [ESLD] or non-ESLD) who developed an ICH in the hospital, (2) patients with ESLD who undergo either operative vs nonoperative management, and (3) patients with ESLD on the liver transplant waitlist who developed an ICH in the hospital. We retrospectively reviewed hospital charts from March 2006 through February 2017 of patients with liver disease and an ICH evaluated by the neurosurgery service at a single academic medical center. The primary outcome was survival. We included a total of 53 patients in this study. The overall survival for patients with an admission diagnosis of liver disease who developed an ICH (n = 29, 55%) in the hospital was 22%. Of those patients with an admission diagnosis of liver disease, 27 patients also had ESLD. Kaplan-Meier analysis found no significant difference in survival for ESLD patients (n = 33, 62%) according to operative status. There were 11 ESLD patients on the liver transplant waitlist. The overall survival for patients with ESLD o...Continue Reading

References

Mar 1, 1988·American Journal of Surgery·G V AranhaH B Greenlee
Jun 1, 1985·Archives of Surgery·R S BlochA J Walt
Aug 1, 1973·The British Journal of Surgery·R N PughR Williams
Sep 1, 1983·American Journal of Surgery·D CastaingH Bismuth
Jan 1, 1981·American Journal of Surgery·H A PittT R Gadacz
Jan 1, 1982·American Journal of Surgery·G V AranhaH B Greenlee
May 1, 1995·Mayo Clinic Proceedings·E F WijdicksR A Krom
Dec 1, 1996·Neurology·E F WijdicksJ L Steers
Oct 23, 1998·Journal of the American College of Surgeons·D SleemanA Livingstone
May 29, 2000·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·W L WangS T Fan
Feb 15, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·P S KamathW R Kim
Feb 25, 2006·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Neal R BarshesJohn A Goss
May 2, 2006·Transplantation Proceedings·G ArdizzoneE Cerutti
Jan 16, 2008·Clinical Neurology and Neurosurgery·Hsin-Hung HuangTsai-Yuan Hsieh
May 16, 2009·Clinics in Liver Disease·Jacqueline G O'LearyLawrence S Friedman
Sep 30, 2010·Developmental Medicine and Child Neurology·Jonathan T KleinmanLori C Jordan
Apr 24, 2012·Neurologia Medico-chirurgica·Katsumi HoyaAkio Hyodo
May 29, 2012·Journal of Neurosurgery·Ching-Chang ChenYin-Cheng Huang
Sep 29, 2015·World Journal of Hepatology·Ching-Chang ChenChun-Nan Yeh
Dec 19, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Neal S ParikhHooman Kamel
Jan 21, 2017·F1000Research·Francesco Paolo RussoAlberto Zanetto

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