Survival patterns in teenagers and young adults with cancer in the United Kingdom: Comparisons with younger and older age groups

European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
Dan StarkC O'Hara

Abstract

We aimed to describe and compare survival in teenagers and young adults (TYAs) with cancer to that of younger children and older adults, to identify sub-populations at greater or lesser risk of death. We compared survival in cancer patients diagnosed in the United Kingdom aged 13-24 years (TYAs) to those aged 0-12 (children) and 25-49 years (adults) using the National Cancer Data Repository. All cases had a first cancer diagnosis between 1st January 2001 and 31st December 2005 with censor date 31st December 2010 or death if earlier. We found six distinct statistically significant survival patterns. In pattern 1, the younger the age-group the better the 1- and 5-year survival (acute lymphoid leukaemia, carcinoma of ovary and melanoma). In pattern 2, TYAs had a worse 5-year survival than both children and young adults (bone and soft tissues sarcomas). In pattern 3, TYAs had a worse 1-year survival but no difference at 5-years (carcinoma of cervix and female breast). In pattern 4, TYAs had better 1-year survival than adults, but no difference at 5 years (carcinoma of liver and intrahepatic bile ducts, germ cell tumours of extra-gonadal sites). In pattern 5, the younger the age-group the better the 5-year survival, but the differen...Continue Reading

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Citations

Jan 13, 2017·Journal of Adolescent and Young Adult Oncology·Simon A PiniDan P Stark
Feb 7, 2017·Journal of Adolescent and Young Adult Oncology·Gemma PughAbigail Fisher
Apr 11, 2018·Journal of Adolescent and Young Adult Oncology·Judith FortmannGemma Pugh
Jul 24, 2018·Journal of Adolescent and Young Adult Oncology·Lesley SmithDan Stark
May 16, 2020·Journal of Adolescent and Young Adult Oncology·Thomas RazeEmmanuel Desandes
Jun 2, 2016·American Society of Clinical Oncology Educational Book·Joseph M UngerArchie Bleyer
Nov 14, 2019·British Journal of Cancer·Klaus RostgaardLisa L Hjalgrim
Mar 29, 2019·Cancer Nursing·Judith FortmannGemma Pugh

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