Survival proteomes: the emerging proteotype of antimicrobial resistance

FEMS Microbiology Reviews
Amber J ParkCezar M Khursigara

Abstract

Antimicrobial resistance is one of the greatest challenges in modern medicine. Infectious diseases that have historically been eliminated with routine antibiotic therapy are now re-emerging as life threatening illnesses. A better understanding of the specific mechanisms that contribute to resistance are required to optimize the treatment of infectious microorganisms and limit the survival of recalcitrant populations. This challenging area of research is made more problematic by the observation that multiple, overlapping, and/or compensatory resistance mechanism are often present within a single bacterial species. High-resolution proteomics has emerged as an effective tool to study antimicrobial resistance as it allows for the quantitative investigation of multiple systems concurrently. Furthermore, the ability to examine extracellular mechanisms of resistance and important post-translational modifications make this research tool well suited for the challenge. This review discusses how proteomics has contributed to the understanding of antimicrobial resistance and focuses on advances afforded by the more recent development of technologies that produce quantitative high-resolution proteomic information. We discuss current strateg...Continue Reading

References

Dec 14, 1979·Biochemical and Biophysical Research Communications·M Manai, A J Cozzone
Feb 13, 2001·Antimicrobial Agents and Chemotherapy·M Arthur, R Quintiliani
Dec 26, 2001·Nucleic Acids Research·T HubbardM Clamp
Jan 28, 2003·Current Opinion in Chemical Biology·Dario E KalumeAkhilesh Pandey
Dec 19, 2003·Nucleic Acids Research·Rolf ApweilerLai-Su L Yeh
Jun 21, 2005·Advanced Drug Delivery Reviews·Peter A Lambert
Mar 16, 2006·Analytical Chemistry·Ralf KrügerWolf D Lehmann
Dec 1, 2007·Nucleic Acids Research·David S WishartMurtaza Hassanali
Sep 23, 2008·Journal of Bacteriology·Que Chi Truong-BolducDavid C Hooper
Oct 27, 2009·Trends in Microbiology·Alain J Cozzone
Mar 9, 2010·Nature Reviews. Microbiology·Dan I Andersson, Diarmaid Hughes
Oct 29, 2010·Tuberculosis·Jocelyne M LewStewart T Cole
Jun 8, 2011·FEMS Microbiology Reviews·José L Martínez, Fernando Rojo
Jun 15, 2011·Journal of Proteomics·Thierry Rabilloud, Cécile Lelong
Aug 31, 2011·Journal of Proteome Research·Jie FengMarc Ouellette
Nov 19, 2011·FEMS Microbiology Reviews·Ivan Mijakovic, Boris Macek
Aug 7, 2012·Molecular & Cellular Proteomics : MCP·Amelia C PetersonJoshua J Coon
Dec 4, 2012·Nucleic Acids Research·Matthew D WhitesideFiona S L Brinkman
Feb 14, 2013·Antimicrobial Agents and Chemotherapy·Song Lin ChuaMichael Givskov
Apr 3, 2013·Nature Methods
Sep 3, 2013·Journal of Proteomics·Joel A CainStuart J Cordwell
Dec 10, 2013·Nucleic Acids Research·Tatiana TatusovaIgor Tolstoy
Jan 9, 2014·PloS One·Patrick M ChongUNKNOWN Canadian Nosocomial Infection Surveillance Program (CNISP)
Feb 4, 2014·The Journal of Antimicrobial Chemotherapy·Sang-Yeop LeeSeung Il Kim
Feb 26, 2014·Journal of Medical Microbiology·Sunanta NabuVirapong Prachayasittikul

❮ Previous
Next ❯

Citations

Apr 12, 2016·Frontiers in Microbiology·Francisco J Pérez-Llarena, Germán Bou
Oct 27, 2016·Biochemical Pharmacology·Çiğdem Yılmaz, Gülay Özcengiz
Jan 27, 2019·Molecular & Cellular Proteomics : MCP·Marie-Laurence LemaySylvain Moineau
May 21, 2019·Therapeutic Advances in Urology·Alicia López Romo, Rodolfo Quirós
Oct 6, 2019·Molecular & Cellular Proteomics : MCP·Florence Roux-DalvaiArnaud Droit
Mar 15, 2020·International Journal of Molecular Sciences·Ernesto PalmaPaola Roncada
Mar 20, 2019·Expert Opinion on Drug Discovery·Vladislav M ChernovRustam I Aminov
Aug 21, 2020·Cell Death & Disease·Caitlyn B BrashearsJason M Held
Dec 1, 2019·Molecular & Cellular Proteomics : MCP·Florence Roux-DalvaiArnaud Droit
Apr 1, 2019·Molecular & Cellular Proteomics : MCP·Marie-Laurence LemaySylvain Moineau
Sep 23, 2021·Scientific Reports·Xudong OuyangJeroen den Hertog

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Related Papers

Revista española de cardiología
Hüseyin Ince, Christoph A Nienaber
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine
A Iwamoto
Acta Clinica Belgica
W E Peetermans, P De Munter
Nihon rinsho. Japanese journal of clinical medicine
Masafumi Seki, Shigeru Kohno
Nihon rinsho. Japanese journal of clinical medicine
Kiyosu Taniguchi
© 2022 Meta ULC. All rights reserved