PMID: 3773980Sep 1, 1986Paper

Susceptibility of clinical isolates of yeasts to anti-fungal agents

Mycopathologia
S M Hussain QadriE G Ramirez

Abstract

The antimicrobial activity of amphotericin B, 5-fluorocytosine, nystatin, clotrimazole and miconazole were compared in vitro against 244 strains of yeasts that had been isolated from clinical specimens. The yeasts used in this study included 20 species of Candida, Cryptococcus, Saccharomyces Geotrichum, Rhodotorula, Torulopsis and Trichosporon. The majority of the strains (78%) had an MIC of less than or equal to 0.5 microgram/ml for amphotericin B, 81% an MIC of less than or equal to 1 microgram/ml for 5-fluorocytosine, 99% less than or equal to 8 micrograms/ml for nystatin, 91%, less than or equal to 8.0 micrograms/ml for clotrimazole and 98% had an MIC of less than or equal to 4.0 for miconazole. Of the anti-fungal agents tested, 5-fluorocytosine and nystatin were found to have the greatest antifungal activity.

References

Aug 1, 1979·Antimicrobial Agents and Chemotherapy·D PappagianisJ S Remington
Jan 1, 1985·Annals of Internal Medicine·J D DickR Saral
May 1, 1974·Annals of Surgery·H H StoneJ Z Cuzzell
Oct 1, 1973·The British Journal of Dermatology·Y M Clayton
Jan 1, 1974·Advances in Applied Microbiology·J M Hamilton-Miller
Dec 1, 1969·The American Journal of the Medical Sciences·A S Klainer, W R Beisel
Aug 1, 1969·The Journal of Infectious Diseases·P D HartJ S Remington
Jan 1, 1983·Chemotherapy·T Bergan, M Vangdal
Aug 1, 1983·Journal of Clinical Microbiology·R GuinetP Ambroise-Thomas
Sep 1, 1981·The American Journal of Medicine·F Meunier-CarpentierD Armstrong
Jul 12, 1965·JAMA : the Journal of the American Medical Association·E M HERSHE J FREIREICH
Oct 1, 1970·Infection and Immunity·S Shadomy
Sep 1, 1948·Journal of Bacteriology·L J Wickerham, K A BURTON
Sep 1, 1948·Journal of Bacteriology·L J WICKERHAN, K A BURTON

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.