PMID: 6404649Feb 7, 1983Paper

Susceptibility of ribosomes of the tetracycline-producing strain of Streptomyces aureofaciens to tetracyclines

FEBS Letters
K MikulíkJ Weiser

Abstract

Ribosomes from cells of Streptomyces aureofaciens producing tetracycline antibiotics (Tc-ribosomes) differ in electrophoretic mobility of ribosomal proteins S2, S10 and L19 from those of the same strain, where the production of tetracyclines was suppressed by changed cultivation conditions (C-ribosomes). Purified tight vacant couples C- and Tc-ribosomes are equally active in the translation of poly(U). Both types of S. aureofaciens ribosomes are more sensitive to tetracycline and chlortetracycline than ribosomes of Escherichia coli in the Phe-tRNA binding and the translation of poly(U).

References

Jan 1, 1979·Molecular & General Genetics : MGG·G Williams, I Smith
Aug 1, 1977·Archives of Biochemistry and Biophysics·J W HersheyJ L Fakunding
Nov 5, 1979·Journal of Molecular Biology·M Peters, M Yarus
Mar 16, 1976·European Journal of Biochemistry·D BarritaultD Hayes
Jun 28, 1972·Journal of Molecular Biology·S Watanabe
Aug 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·S Sarkar, R E Thach
Mar 16, 1981·Biochemical and Biophysical Research Communications·J WeiserL Bosch
Dec 31, 1982·Biochimica Et Biophysica Acta·K MikulíkA Jiránová
Mar 1, 1980·Plasmid·B MendezS B Levy
Jun 16, 1981·Biochemical and Biophysical Research Communications·H YamamotoH Umezawa

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Citations

Nov 19, 2010·Journal of Industrial Microbiology & Biotechnology·Jan Nešvera
Dec 3, 1984·European Journal of Biochemistry·K MikulíkA Jiránová
Nov 24, 1999·Biochemical and Biophysical Research Communications·K MikulíkV Bêhal
May 29, 1986·Biochemical and Biophysical Research Communications·I Janda, K Mikulík
Oct 1, 1992·Clinical Microbiology Reviews·B S SpeerA A Salyers

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