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Susceptibility to tuberculosis: composition of tuberculous granulomas in Thorbecke and outbred New Zealand White rabbits

Veterinary Immunology and Immunopathology

Dec 25, 2007

Susana E MendezYukari C Manabe

Abstract

We sought to characterize the lung cellular immune responses to inhaled Mycobacterium tuberculosis (Mtb) of the susceptible inbred Thorbecke rabbit (the genomically sequenced strain, now unavailable) and compare it to outbred, Mtb-resistant, New Zealand White rabbits. Using Mtb CDC1551,...read more

Mentioned in this Paper

Real-Time Polymerase Chain Reaction
Immune Response
Necrosis
T-Lymphocyte
ITGAX wt Allele
Antigen-Presenting Cells
Lung
Tuberculosis
Lymphocytes as Percentage of Blood Leukocytes (Lab Test)
Cavia
Paper Details
References
  • References9
  • Citations8
1
  • References9
  • Citations8
1

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Susceptibility to tuberculosis: composition of tuberculous granulomas in Thorbecke and outbred New Zealand White rabbits

Veterinary Immunology and Immunopathology

Dec 25, 2007

Susana E MendezYukari C Manabe

PMID: 18155300

DOI: 10.1016/j.vetimm.2007.11.006

Abstract

We sought to characterize the lung cellular immune responses to inhaled Mycobacterium tuberculosis (Mtb) of the susceptible inbred Thorbecke rabbit (the genomically sequenced strain, now unavailable) and compare it to outbred, Mtb-resistant, New Zealand White rabbits. Using Mtb CDC1551,...read more

Mentioned in this Paper

Real-Time Polymerase Chain Reaction
Immune Response
Necrosis
T-Lymphocyte
ITGAX wt Allele
Antigen-Presenting Cells
Lung
Tuberculosis
Lymphocytes as Percentage of Blood Leukocytes (Lab Test)
Cavia

Similar Papers Found In These Feeds

Inferring Cell Interactions: Human Lymph Nodes

Lymph nodes are part of the immune system and are spread throughout the body, draining lymph from various organs. Generating a spatial atlas of healthy human lymph nodes through single cell transcriptomics will gain insight into their complex biology. Discover the latest research on inferring cell interactions in human lymph nodes here.

Delayed Hypersensitivity

Delayed hypersensitivity reactions are inflammatory reactions initiated by mononuclear leukocytes. Delayed hypersensitivity is a major mechanism of defense against various intracellular pathogens, including mycobacteria, fungi, and certain parasites, and it occurs in transplant rejection and tumor immunity. Discover the latest research on delayed hypersensitivity here.

Related Papers

Infection and Immunity

Susceptibility to tuberculosis: clues from studies with inbred and outbred New Zealand White rabbits

Infection and ImmunityFebruary 24, 2004
Susan E DormanYukari C Manabe
Paper Details
References
  • References9
  • Citations8
1
  • References9
  • Citations8
1
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