Sustainable vaccine development: a vaccine manufacturer's perspective

Current Opinion in Immunology
Rino Rappuoli, Emmanuel Hanon

Abstract

Vaccination remains the most cost-effective public health intervention after clean water, and the benefits impressively outweigh the costs. The efforts needed to fulfill the steadily growing demands for next-generation and novel vaccines designed for emerging pathogens and new indications are only realizable in a sustainable business model. Vaccine development can be fast-tracked through strengthening international collaborations, and the continuous innovation of technologies to accelerate their design, development, and manufacturing. However, these processes should be supported by a balanced project portfolio, and by managing sustainable vaccine procurement strategies for different types of markets. Collectively this will allow a gradual shift to a more streamlined and profitable vaccine production, which can significantly contribute to the worldwide effort to shape global health.

Citations

Sep 3, 2019·Expert Review of Vaccines·Francesca MicoliRoberto Adamo
Apr 16, 2020·Applied Microbiology and Biotechnology·Gwendal GränicherUdo Reichl
May 18, 2021·SN Comprehensive Clinical Medicine·Sara MomtazmaneshNima Rezaei
Aug 28, 2021·Globalization and Health·Catherine DecouttereNico Vandaele
Aug 30, 2021·Trends in Pharmacological Sciences·Shruthi Polla RaviArghya Paul

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Clinical Trials Mentioned

NCT01755598
NCT02646371
NCT03049488
NCT03275389
NCT02927873

Software Mentioned

GAVI
PERISCOPE

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