Sustained lung inflation at birth via short binasal prong in very low birth weight preterm infants: A retrospective study

Pediatric Pulmonology
Mehmet BuyuktiryakiCuneyt Tayman

Abstract

It is believed, that sustained lung inflation (SLI) at birth in preterm infants reduces the need for mechanical ventilation (MV) and improves respiratory outcomes. The aim of this study was to compare need for MV in preterm infants at high risk for respiratory distress syndrome (RDS) after prophylactic SLI via short binasal prongs at birth combined with early nasal continuous positive airway pressure (nCPAP) versus nCPAP alone. Medical records of infants born at 260/7 to 296/7 weeks gestation through 2015 and 2017 were retrospectively assessed. Infants who get sustained inflations at 25 cmH2 O pressure for 15 s following delivery via binasal short prongs comprised the study group. Gestational age matched infants who was supported solely with nCPAP (6 cmH2 O PEEP) comprised the control group. Early rescue surfactant (200 mg/kg poractant alfa) was delivered using the less invasive surfactant administration technique in infants with established RDS. A total of 215 infants were analyzed. Fewer infants in the SLI group required MV within the first 72 h of life compared to the control group (25.7% vs 56.9%, P < 0.001). In multiple logistic regression analysis, SLI emerged as an independent factor for reduced MV need. Bronchopulmonary...Continue Reading

References

Jun 13, 2001·American Journal of Respiratory and Critical Care Medicine·A H Jobe, E Bancalari
Sep 19, 2003·Journal of Perinatology : Official Journal of the California Perinatal Association·Michele C WalshAvroy Fanaroff
May 3, 2005·Archives of Disease in Childhood. Fetal and Neonatal Edition·A E HarlingC W Yoxall
Sep 27, 2005·The Journal of Pediatrics·Amer AmmariRichard A Polin
Feb 3, 2006·Pediatrics·UNKNOWN Section on Ophthalmology American Academy of PediatricsUNKNOWN American Association for Pediatric Ophthalmology and Strabismus
Feb 15, 2008·The New England Journal of Medicine·Colin J MorleyUNKNOWN COIN Trial Investigators
Jun 18, 2008·Journal of Perinatology : Official Journal of the California Perinatal Association·R Ramanathan, S Sardesai
Jul 2, 2010·Archives of Disease in Childhood. Fetal and Neonatal Edition·Kim SchillemanArjan B te Pas
Aug 5, 2011·Pediatric Pulmonology·Amir Kugelman, Manuel Durand
Oct 30, 2012·The Journal of Pediatrics·Kim SchillemanArjan B te Pas
Jan 1, 2014·Pediatrics·UNKNOWN Committee on Fetus and Newborn, UNKNOWN American Academy of Pediatrics
Jul 21, 2014·The Journal of Pediatrics·Jeroen J van VonderenArjan B te Pas
Jan 1, 2015·Archives of Disease in Childhood. Fetal and Neonatal Edition·Georg M SchmölzerPo-Yin Cheung
Jan 28, 2015·Pediatrics·Gianluca ListaUNKNOWN SLI Trial Investigators
Mar 1, 2016·Seminars in Fetal & Neonatal Medicine·G ListaL J I Zimmermann
Jun 3, 2016·Neonatology·Gianluca ListaFrancesca Castoldi
Jul 8, 2016·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Mohamed S El-ChimiDina M Shinkar
Nov 14, 2016·Clinics in Perinatology·Elizabeth E Foglia, Arjan B Te Pas
Aug 11, 2017·European Journal of Pediatrics·Gianluca ListaFernando R Moya

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.