Sustained pre-hypertensive blood pressure and incident atrial fibrillation: the Multi-Ethnic Study of Atherosclerosis

Journal of the American Society of Hypertension : JASH
Wesley T O'NealDavid Herrington

Abstract

The association between sustained pre-hypertension and atrial fibrillation (AF) has not been thoroughly examined. This study included 5311 participants (mean age 62 ± 10 years; 47% male; 42.9% non-whites) from the Multi-Ethnic Study of Atherosclerosis. Sustained exposure was based on 2 or more visits within the same blood pressure category (optimal, <120/80 mm Hg; pre-hypertension, 120-139/80-89 mm Hg; hypertension, ≥140/90 mm Hg or antihypertensive medication use) during visits 1, 2, and 3. Cox regression was used to compute hazard ratios (HR) and 95% confidence intervals (CI) for the association between blood pressure category and AF. Over a median follow-up of 5.3 years, 182 (3.4%) participants developed AF. Pre-hypertension and hypertension were associated with an increased risk of AF compared with participants who had optimal blood pressure (optimal: HR, 1.0; referent; pre-hypertension: HR, 1.8; 95% CI, 1.004-3.2; hypertension: HR, 2.6; 95% CI, 1.6-4.4). Sustained pre-hypertension is associated with an increased risk of AF.

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Citations

Sep 16, 2015·European Heart Journal·Chrishan Joseph NalliahJonathan M Kalman
Jan 20, 2018·Circulation Research·Paolo VerdecchiaGianpaolo Reboldi
Mar 10, 2020·Circulation·Mina K ChungUNKNOWN American Heart Association Electrocardiography and Arrhythmias Committee and Exercise, Cardiac Rehabilitation, and Secondary
May 5, 2020·Hypertension·Elsayed Z SolimanCora E Lewis
Oct 14, 2018·Current Cardiology Reports·Chrishan J NalliahJonathan M Kalman
Aug 4, 2019·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Satoshi UmemuraNobuhito Hirawa
Feb 1, 2021·Cardiac Electrophysiology Clinics·Dennis H LauMohammad Shenasa
May 1, 2021·Journal of Clinical Medicine·Hilde EspnesEkaterina Sharashova
Aug 18, 2021·International Journal of Hygiene and Environmental Health·Chieh-Ming WuChi Song

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