PMID: 9636184Jun 24, 1998Paper

Su(UR)ES: a gene suppressing DNA underreplication in intercalary and pericentric heterochromatin of Drosophila melanogaster polytene chromosomes

Proceedings of the National Academy of Sciences of the United States of America
E S BelyaevaDmitry E Koryakov

Abstract

A genetic locus suppressing DNA underreplication in intercalary heterochromatin (IH) and pericentric heterochromatin (PH) of the polytene chromosomes of Drosophila melanogaster salivary glands, has been described. Found in the In(1)scV2 strain, the mutation, designated as Su(UR)ES, was located on chromosome 3L at position 34. 8 and cytologically mapped to region 68A3-B4. A cytological phenotype was observed in the salivary gland chromosomes of larvae homozygous and hemizygous for Su(UR)ES: (i) in the IH regions, that normally are incompletely polytenized and so they often break to form "weak points," underreplication is suppressed, breaks and ectopic contacts disappear; (ii) the degree of polytenization in PH grows higher. That is why the regions in chromosome arm basements, normally beta-heterochromatic, acquire a distinct banding pattern, i. e., become euchromatic by morphological criteria; (iii) an additional bulk of polytenized material arises between the arms of chromosome 3 to form a fragment with a typical banding pattern. Chromosome 2 PH reveals additional alpha-heterochromatin. Su(UR)ES does not affect the viability, fertility, or morphological characters of the imago, and has semidominant expression in the heterozygot...Continue Reading

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Citations

Oct 13, 2005·Chromosoma·Julie A Wallace, Terry L Orr-Weaver
Sep 20, 2011·Chromosoma·Tin Tin Su
Aug 16, 2008·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·E N AndreyevaI F Zhimulev
Feb 23, 2011·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Dmitry E KoryakovGunter Reuter
Jan 21, 2011·Nucleic Acids Research·Nickolai A TchurikovYuri V Kravatsky
May 4, 2010·Genome Research·Michaela SchwaigerDirk Schübeler
Dec 24, 2010·Genome Research·Jared NordmanTerry L Orr-Weaver
Dec 11, 2007·Doklady. Biochemistry and Biophysics·O V PosukhI F Zhimulev
Aug 12, 2005·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Harald BiessmannJames M Mason
Jan 10, 2012·Development·Jared Nordman, Terry L Orr-Weaver
Dec 12, 2012·Development·Donald T Fox, Robert J Duronio
May 3, 2014·PLoS Genetics·Roberta L HannibalJulie C Baker
Jan 7, 2014·PloS One·Natalya G AndreyenkovaElena S Belyaeva
Jul 21, 2007·Proceedings of the National Academy of Sciences of the United States of America·Eugenia N AndreyevaIgor F Zhimulev
Jun 2, 2005·Proceedings of the National Academy of Sciences of the United States of America·Stepan N BelyakinIgor F Zhimulev
Jul 10, 2014·Genome Génome / Conseil National De Recherches Canada·Sachin ThapaShailika Chhetri
Sep 19, 2015·Nucleic Acids Research·Roland F HoffmannPeter M Lansdorp
Mar 1, 2006·Current Opinion in Genetics & Development·Michaela Schwaiger, Dirk Schübeler
Jun 11, 2015·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Jared T Nordman, Terry L Orr-Weaver
Nov 18, 2003·Annual Review of Genetics·Laura A Lee, Terry L Orr-Weaver
May 27, 2015·The Journal of Cell Biology·Kevin P Schoenfelder, Donald T Fox
Dec 2, 2014·Cell Reports·Jared T NordmanTerry L Orr-Weaver
Nov 19, 2004·International Review of Cytology·I F ZhimulevE N Andreyeva
Oct 28, 2003·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Igor F Zhimulev, Elena S Belyaeva

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