Abstract
Positron emission tomography (PET) and the maximum standardized uptake value (SUVmax) is a useful technique for assessing malignant tumors. Measurements of SUVmax in multiple lesions per patient frequently require many time-consuming procedures. To address this issue, we designed a novel interface named SUV Navigator (SUVnavi), and the purpose of this study was to investigate its utility. We measured SUVmax in 661 lesions from 100 patients with malignant tumors. Diagnoses and SUVmax measurements were made with SUVnavi, 2D, and 3D measurements. SUV measurement accuracy in each method were also evaluated. The average reduction in time with SUVnavi versus 2D was 53.8% and 3D was 37.5%; time required with SUVnavi was significantly shorter than with 2D and 3D (P < 0.001 and P < 0.001, respectively). The time reduction and lesion number had a positive correlation (P < 0.001 and P < 0.001, respectively). SUVmax agreed with precise SUVmax in all lesions measured with SUVnavi and 3D but in only 466 of 661 lesions (70.5%) measured with 2D. SUVnavi may be useful for rapid [18F]-fluorodeoxyglucose positron emission tomography/computed tomography ([18F]-FDG PET/CT) image interpretation without reducing the accuracy of SUVmax measurement.
References
Feb 16, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·H YoungP Price
Oct 20, 2004·Seminars in Nuclear Medicine·Heiko Schöder, Steven M Larson
Oct 18, 2008·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Cheolwon SuhBong-Jae Lee
Dec 19, 2008·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Tohru ShigaNagara Tamaki
Apr 3, 2009·Annals of Nuclear Medicine·Atsushi NambuTsutomu Araki
Apr 10, 2009·The Oncologist·Martin Allen-Auerbach, Wolfgang A Weber
Jun 24, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Richard L WahlMartin A Lodge
Aug 7, 2009·Nuclear Medicine Communications·Maroun KaramLieselot M Brepoels
May 1, 2010·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Yohei ImamuraHisamichi Aizawa
Sep 9, 2010·Annals of Nuclear Medicine·Kyoichi KairaNobuyuki Yamamoto
Dec 7, 2010·Acta Clinica Belgica·D J De MaeseneerS W H Rottey
Mar 16, 2011·Annals of Nuclear Medicine·Keishi MakinoJun-ichi Kuratsu
Apr 23, 2011·International Journal of Hematology·Dai ChiharaYasuo Morishima
Apr 27, 2011·Blood·René-Olivier CasasnovasUNKNOWN Groupe d'étude des lymphomes de l'adulte (GELA)
Jan 14, 2012·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Jose L Lopez GuerraZhongxing Liao
Jan 24, 2012·Academic Radiology·Lijuan YuJingshu Geng
Jun 12, 2012·Seminars in Nuclear Medicine·Sze Ting LeeAndrew M Scott
Aug 7, 2012·Surgery Today·Tomoyoshi TakenakaYoshihiko Maehara
Jan 31, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Chang-Bae KongSoo-Yong Lee
Feb 19, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Anna Margherita MaffioneDomenico Rubello
Dec 19, 2013·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Atsuya TakedaEtsuo Kunieda
Feb 26, 2014·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Cédric RossiRené-Olivier Casasnovas