SV40 T antigen binds specifically to a cellular 53 K protein in vitro

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SV40 T antigen binds specifically to a cellular 53 K protein in vitro

Abstract

References

T antigen binds to simian virus 40 DNA at the origin of replication.

Regulation of tumor antigen synthesis by simain virus 40 gene A.

The binding site on SV40 DNA for a T antigen-related protein

Biological activity of purified simian virus 40 T antigen proteins

Extraction and fingerprint analysis of simian virus 40 large and small T-antigens

T antigen is bound to a host protein in SV40-transformed cells

Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

Mutational analysis of the simian virus 40 replicon: pseudorevertants of mutants with a defective replication origin

Simian virus 40 deoxyribonucleic acid synthesis: the viral replicon

Monoclonal antibodies against simian virus 40 T antigens: evidence for distinct sublcasses of large T antigen and for similarities among nonviral T antigens

Complex of simian virus 40 large-T antigen and host 53,000-molecular-weight protein in monkey cells

Association of a murine 53,000-dalton phosphoprotein with simian virus 40 large-T antigen in transformed cells

Regulation of simian virus 40 early transcription in vitro by a purified tumor antigen

Construction and analysis of simian virus 40 origins defective in tumor antigen binding and DNA replication

Detection of a common feature in several human tumor cell lines--a 53,000-dalton protein

Lymphocyte stimulation: concanavalin A induces the expression of a 53K protein

Citations

Transcriptional activation is not responsible for increased levels of autonomously expressed simian virus 40 T-antigen in herpes simplex virus-infected cells

Apoptosis, cancer and the p53 tumour suppressor gene

The cell cycle and the retinoblastoma protein family

The simian virus 40 large tumor antigen

Protein-protein interactions in high molecular weight forms of the transformation-related phosphoprotein p53

p53 in growth control and neoplasia

Kinetic mechanism of p53 oncogenic mutant aggregation and its inhibition.

Nonselective expression of simian virus 40 large tumor antigen fragments in mouse cells

The p53 protein is an unusually shaped tetramer that binds directly to DNA

Expression of SV40 virus large T antigen by recombinant adenoviruses activates proliferation of corneal endothelium in vitro

Wild type p53 transcriptionally represses the SALL2 transcription factor under genotoxic stress.

Epstein-Barr virus-associated gastric lymphomas are distinct from mucosa-associated lymphoid tissue-type lymphomas: genetic abnormalities of p53 gene

Formation of stable p53 homotetramers and multiples of tetramers

Activity of the retinoblastoma family proteins, pRB, p107, and p130, during cellular proliferation and differentiation

Regions of SV40 large T antigen necessary for oligomerization and complex formation with the cellular oncoprotein p53

Primate's p53 inhibits SV40 DNA replication in vitro

Effects of gamma-linolenic acid and arachidonic acid on cell cycle progression and apoptosis induction in normal and transformed cells

Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene

The murine p53 protein blocks replication of SV40 DNA in vitro by inhibiting the initiation functions of SV40 large T antigen

An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120

P53-transformation-related protein: kinetics of synthesis and accumulation in SV40-infected primary mouse kidney cell cultures.

Efficient synthesis of adeno-associated virus structural proteins requires both adenovirus DNA binding protein and VA I RNA

A set of stage-dependent embryonic antigens expressed in cell cultures of BALB/c mouse embryos and in transformed cell lines.

Adenovirus E1-transformed cells grow despite the continuous presence of transcriptionally active p53

Correlation of metabolic stability and altered quaternary structure of oncoprotein p53 with cell transformation.

Mutants with changes within or near a hydrophobic region of simian virus 40 large tumor antigen are defective for binding cellular protein p53

Murine gammaherpesvirus-68 LANA and SOX homologs counteract ATM-driven p53 activity during lytic viral replication

Effect of oral isotretinoin on the nucleo-cytoplasmic distribution of FoxO1 and FoxO3 proteins in sebaceous glands of patients with acne vulgaris

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation

Human polyomavirus BKV transcriptionally activates DNA methyltransferase 1 through the pRb/E2F pathway

Transforming genes and gene products of polyoma and SV40

Immunoaffinity chromatography of a cellular tumor antigen from mouse neuroblastoma cells

The role of tetramerization in p53 function

p53: key conductor of all anti-acne therapies

Fifty Years of JC Polyomavirus: A Brief Overview and Remaining Questions.

p53 tetramerization: at the center of the dominant-negative effect of mutant p53.

Interactions between adenovirus proteins and the p53 pathway: the development of ONYX-015

Mechanistic insights into p53-promoted RNA-RNA annealing

Characterization of mutant p53-hsp72/73 protein-protein complexes by transient expression in monkey COS cells.

Inactivation of the retinoblastoma susceptibility protein is not sufficient for the transforming function of the conserved region 2-like domain of simian virus 40 large T antigen

Oligomerization of simian virus 40 large T antigen is not necessarily repressed by temperature-sensitive A gene lesions

Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis.

Self-assembly of simian virus 40 large T antigen oligomers by divalent cations

Study of the functional activities concomitantly retained by the 115,000 Mr super T antigen, an evolutionary variant of simian virus 40 large T antigen expressed in transformed rat cells

Adeno-associated virus proteins: origin of the capsid components

The tumor suppressor p53

An oligomeric form of simian virus 40 large T-antigen is immunologically related to the cellular tumor antigen p53

Evolutionary conservation of the biochemical properties of p53: specific interaction of Xenopus laevis p53 with simian virus 40 large T antigen and mammalian heat shock proteins 70

Two distinct regions of the murine p53 primary amino acid sequence are implicated in stable complex formation with simian virus 40 T antigen

Oligomerization of oncoprotein p53

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