SV40 transcription terminators stabilize the activity of regulatory elements in Drosophila melanogaster

Doklady. Biochemistry and Biophysics
D A ChetverinaM M Erokhin

Abstract

To ensure stable operation of transgenic systems and maintain reporter gene expression at a certain level, it is necessary to search for the conditions that protect the activity of regulatory elements. In this study, we have shown that the SV40 transcription terminators flanking the transgene protect enhancers and silencers of Drosophila and ensure their efficient functioning.

References

Mar 26, 2005·Science·Jill ChengThomas R Gingeras
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Mar 30, 2010·Trends in Biochemical Sciences·Lluís Morey, Kristian Helin
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Nov 28, 2013·Epigenetics & Chromatin·Maksim ErokhinDarya Chetverina

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Citations

Apr 24, 2019·Doklady. Biochemistry and Biophysics·M M ErokhinD A Chetverina

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