Swelling-induced taurine transport: relationship with chloride channels, anion-exchangers and other swelling-activated transport pathways

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology
David B Shennan

Abstract

Cells have to regulate their volume in order to survive. Moreover, it is now evident that cell volume per se and the membrane transport processes which regulate it, comprise an important signalling unit. For example, macromolecular synthesis, apoptosis, cell growth and hormone secretion are all influenced by the cellular hydration state. Therefore, a thorough understanding of volume-activated transport processes could lead to new strategies being developed to control the function and growth of both normal and cancerous cells. Cell swelling stimulates the release of ions such as K(+) and Cl(-) together with organic osmolytes, especially the beta-amino acid taurine. Despite being the subject of intense research interest, the nature of the volume-activated taurine efflux pathway is still a matter of controversy. On the one hand it has been suggested that osmosensitive taurine efflux utilizes volume-sensitive anion channels whereas on the other it has been proposed that the band 3 anion-exchanger is a swelling-induced taurine efflux pathway. This article reviews the evidence for and against a role of anion channels and exchangers in osmosensitive taurine transport. Furthermore, the distinct possibility that neither pathway is invol...Continue Reading

References

Dec 1, 1992·The American Journal of Physiology·U Banderali, G Roy
Apr 1, 1992·The American Journal of Physiology·Z I Cabantchik, R Greger
Apr 1, 1991·The Journal of Membrane Biology·R Sánchez OleaM Cereijido
Jan 1, 1992·Physiological Reviews·R J Huxtable
Sep 16, 1991·Neuroscience Letters·R Sanchez-OleaH Pasantes-Morales
Apr 1, 1989·Physiological Reviews·E K Hoffmann, L O Simonsen
Jan 1, 1987·The Journal of Membrane Biology·D A FinchamJ D Young
May 1, 1983·The Journal of Physiology·E K Hoffmann, I H Lambert
Oct 26, 1995·Nature·J R MoormanL R Jones
Nov 1, 1995·The American Journal of Physiology·R Sánchez-OleaH Pasantes-Morales
Dec 1, 1994·The Journal of Membrane Biology·I H Lambert, E K Hoffmann
Jan 1, 1995·International Review of Cytology·E K Hoffmann, P B Dunham
May 1, 1995·The Journal of Physiology·A C Hall
Dec 1, 1993·The American Journal of Physiology·P S Jackson, K Strange
Jul 1, 1993·The American Journal of Physiology·K StrangeR Putnam
Feb 1, 1996·The Biochemical Journal·D Häussinger
Mar 1, 1996·The American Journal of Physiology·K StrangeP S Jackson
Sep 1, 1996·The American Journal of Physiology·L J GaliettaO Zegarra-Moran
Aug 1, 1996·Journal of Neurophysiology·S BasavappaJ C Ellory
Feb 1, 1997·The American Journal of Physiology·T VoetsB Nilius
May 1, 1997·The American Journal of Physiology·C Conejero
Jul 1, 1997·The Journal of Membrane Biology·K Kirk
Jun 1, 1997·The American Journal of Physiology·J MoránH Pasantes-Morales
Jul 1, 1997·The American Journal of Physiology·L J GaliettaO Zegarra-Moran
Jul 1, 1997·The American Journal of Physiology·V G ManolopoulosB Nilius
Oct 8, 1997·The American Journal of Physiology·A StutzinF V Sepúlveda
Dec 11, 1997·The Journal of Experimental Zoology·N Ballatori, J L Boyer
Feb 11, 1998·Physiological Reviews·F LangD Häussinger
Mar 11, 1998·Acta Physiologica Scandinavica·D T Calvert, D B Shennan
May 23, 1998·European Journal of Pharmacology·D SongJ W Phillis
Oct 8, 1998·Contributions to Nephrology·H K Kimelberg, A A Mongin
May 18, 1999·The American Journal of Physiology·A A MonginH K Kimelberg
Sep 14, 1999·The American Journal of Physiology·A StutzinF V Sepúlveda
Nov 11, 1999·Neurochemical Research·H Pasantes-MoralesO Quesada
Apr 20, 2000·Biochimica Et Biophysica Acta·M Morales-MuliaJ Morán
Jul 14, 2000·Physiological Reviews·D B Shennan, M Peaker

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Citations

Feb 25, 2010·Apoptosis : an International Journal on Programmed Cell Death·Qi-Ren HuangMing He
Jan 21, 2009·Nature Reviews. Drug Discovery·Alan S Verkman, Luis J V Galietta
Dec 5, 2015·Pflügers Archiv : European journal of physiology·Thomas J JentschFelizia K Voss
Dec 17, 2009·Neuroscience·H Pasantes-Morales, S Cruz-Rangel
Oct 17, 2009·Neuroscience Letters·Fèlix JunyentCarme Auladell
Jun 4, 2008·Journal of Neurochemistry·Stephen K FisherAnne M Heacock
Nov 18, 2008·Journal of Neurochemistry·Daniel J FosterStephen K Fisher
Jan 19, 2010·Hippocampus·Fèlix JunyentCarme Auladell
Apr 26, 2012·European Journal of Immunology·Susanne KaeslerTilo Biedermann
Feb 4, 2011·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Osvaldo CharaPablo J Schwarzbaum
Oct 6, 2009·Journal of Neurochemistry·Erika Vázquez-JuárezHerminia Pasantes-Morales
Apr 2, 2016·Nature Reviews. Molecular Cell Biology·Thomas J Jentsch
Jul 1, 2016·Molecular Pharmacology·Herminia Pasantes-Morales
Jun 22, 2011·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Cai TangFlorian Lang
Dec 20, 2011·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Ian Henry Lambert, Daniel Bloch Hansen
Jan 30, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Martine AvellaPhilippe Poujeol
Jan 8, 2016·Pflügers Archiv : European journal of physiology·Stine F PedersenBernd Nilius

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