Swine influenza (H1N1) and acute appendicitis

Heart & Lung : the Journal of Critical Care
Burke A CunhaNicole Durie

Abstract

During the swine influenza (H1N1) pandemic that began in 2009, many hospitalized adults had gastrointestinal symptoms. The most common symptoms associated with swine influenza (H1N1) were nausea, vomiting, or diarrhea. In the experience of the authors, swine influenza was not complicated by abdominal pain. There are a wide variety of infectious and non-infectious disorders that may present with a pain in the right lower quadrant, mimicking appendicitis, ie, pseudoappendicitis. Influenza predisposes to some types of bacterial infection, eg, influenza pneumonia may be complicated by simultaneous Staphylococcus aureus community-acquired pneumonia or subsequent community-acquired pneumonia due to Haemophilus influenzae or Streptococcus pneumoniae. It remains unclear if there is direct involvement of the appendix, ie, pseudoappendicitis as occurs with measles or if influenza itself somehow predisposes to increased frequency/severity of bacterial appendicitis. German clinicians first noted an increased incidence of acute appendicitis in children/young adults with influenza. The American and British cases of influenza and acute appendicitis compared to age-matched controls with more severe and of delayed onset/complicated by appendici...Continue Reading

References

Jul 1, 1970·American Journal of Diseases of Children·W M Liebman, J W St Geme
Nov 14, 1998·Pediatric Emergency Care·P M AdcockG S Marshall
Feb 23, 2010·Infectious Disease Clinics of North America·Burke A Cunha

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Citations

Mar 31, 2015·BMJ Case Reports·Christos PlatarasEfstratios Christianakis
Apr 9, 2013·Indian Journal of Pediatrics·Poonam MehtaSushil Kumar Kabra
Oct 1, 2013·Expert Review of Anti-infective Therapy·Bettina LöfflerGeorg Peters
Apr 20, 2013·Pediatrics and Neonatology·Chang-Wei HsuehChin-Pyng Wu
May 28, 2020·World Journal of Surgery·James TankelPetachia Reissman

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