Switchable DNA wire: deposition-stripping of copper nanoclusters as an "ON-OFF" nanoswitch

Scientific Reports
Xiaoli ZhuGenxi Li

Abstract

Today, a consensus that DNA working as a molecular wire shows promise in nanoscale electronics is reached. Considering that the "ON-OFF" switch is the basis of a logic circuit, the switch of DNA-mediated charge transport (DNA CT) should be conquered. Here, on the basis of chemical or electrochemical deposition and stripping of DNA-templated copper nanoclusters (CuNCs), we develop an "ON-OFF" nanoswitch for DNA CT. While CuNCs are deposited, the DNA CT is blocked, which can be also recovered after stripping the CuNCs. A switch cycle can be completed in a few seconds and can be repeated for many times. Moreover, by regulating the amount of reagents, deposition/stripping time, applied potential, etc., the switch is adjustable to make the wire at either an "ON-OFF" state or an intermediate state. We believe that this concept and the successful implementation will promote the practical application of DNA wire one step further.

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Citations

Aug 5, 2017·Chembiochem : a European Journal of Chemical Biology·Arun Richard Chandrasekaran
Jan 28, 2021·Analytical and Bioanalytical Chemistry·Wenxing LiHui Huang

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Methods Mentioned

BETA
scanning tunnelling microscopy
atomic force microscopy
electrophoresis
electron scattering
surface electron scattering
AFM

Software Mentioned

Nova

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